User profiles for Khalid Majid Fazili

Khalid Majid Fazili

University of Kashmir
Verified email at kashmiruniversity.ac.in
Cited by 1641

[PDF][PDF] Plant protease inhibitors: a defense strategy in plants

H Habib, KM Fazili - Biotechnol. Mol. Biol. Rev, 2007 - academicjournals.org
Proteases, though essentially indispensable to the maintenance and survival of their host
organisms, can be potentially damaging when overexpressed or present in higher …

Ameliorated effects of green tea extract on lead induced liver toxicity in rats

EE Mehana, ARMA Meki, KM Fazili - Experimental and toxicologic …, 2012 - Elsevier
In the present study, the effect of green tea extract (GTE) on lead induced toxicity was studied
in Sprague–Dawley rats. Four groups of rats were used in the study. Lead and GTE was …

Fusobacterium nucleatum, inflammation, and immunity: the fire within human gut

…, AY Miskeen, YM Hazari, S Asrafuzzaman, KM Fazili - Tumor Biology, 2016 - Springer
Fusobacterium nucleatum is an identified proinflammatory autochthonous bacterium implicated
in human colorectal cancer. It is also abundantly found in patients suffering from chronic …

The molecular mechanism and functional diversity of UPR signaling sensor IRE1

…, O Qadri, A Bashir, N Hilal, S Rader, KM Fazili - Life Sciences, 2021 - Elsevier
The endoplasmic reticulum is primarily responsible for protein folding and maturation.
However, the organelle is subject to varied stress conditions from time to time, which lead to the …

Alpha-1-antitrypsin deficiency: Genetic variations, clinical manifestations and therapeutic interventions

…, NN Shah, E Haq, J Teckman, KM Fazili - … Research/Reviews in …, 2017 - Elsevier
Alpha-1-antitrypsin (AAT) is an acute phase secretory glycoprotein that inhibits neutrophil
proteases like elastase and is considered as the archetype of a family of structurally related …

Synthesis and biological evaluation of novel 3-O-tethered triazoles of diosgenin as potent antiproliferative agents

Y Mohammad, KM Fazili, KA Bhat, T Ara - Steroids, 2017 - Elsevier
Diosgenin, a promising anticancer steroidal sapogenin, was isolated from Dioscorea deltoidea.
Keeping its stereochemistry rich architecture intact, a scheme for the synthesis of novel …

Emerging tale of UPR and cancer: an essentiality for malignancy

YM Hazari, A Bashir, EU Haq, KM Fazili - Tumor Biology, 2016 - Springer
A set of cellular response to counter any alteration in homeostasis of a cell originating at
endoplasmic reticulum is collectively termed as unfolded protein response (UPR). It initially is …

Bioefficacy potential of different genotypes of walnut Juglans regia L.

UN Shah, JI Mir, N Ahmed, S Jan, KM Fazili - Journal of food science and …, 2018 - Springer
The purpose of investigation was to assess the phytochemical and nutraceutical of walnut in
leaf extracts through diverse quantitative and qualitative phytochemical tests followed by …

Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome

…, S Ashraf, M Nabi, F Rashid, KM Fazili… - Diabetes & Metabolic …, 2019 - Elsevier
Aims PCOS is associated with various immediate and long term health complications. The
aim of this study was to investigate the association of serum fasting insulin concentration with …

[HTML][HTML] Novel variants of SERPIN1A gene: interplay between alpha1-antitrypsin deficiency and chronic obstructive pulmonary disease

…, N Hilal, M Banday, S Asrafuzzaman, KM Fazili - Respiratory …, 2016 - Elsevier
Alpha1-antitrypsin (AAT) is one of the major circulating anti-protease whose levels in
circulation are raised during excessive amount of proteases, especially neutrophil elastase (NE) …