Ionic currents and the network-driven patterns they generate differ in immature and adult
neurons: The developing brain is not a “small adult brain.” One of the most investigated …

Despite a rather long migratory journey, interneurons are functional before vertically
migrating pyramidal neurons and they constitute the source and target of the first functional …

Adult brain networks generate a wide range of oscillations. Some of these are behaviourally
relevant, whereas others occur during seizures and other pathological conditions. This …

We report that the oxytocin-mediated neuroprotective γ-aminobutyric acid (GABA) excitatory-inhibitory
shift during delivery is abolished in the valproate and fragile X rodent models of …

We report a signaling mechanism in rats between mother and fetus aimed at preparing fetal
neurons for delivery. In immature neurons, γ-aminobutyric acid (GABA) is the primary …

We asked whether GABA A and NMDA receptors may act in synergy in neonatal hippocampal
slices, at a time when GABA exerts a depolarizing action. The GABA A receptor agonist …

The immature brain is prone to seizures but the underlying mechanisms are poorly
understood. We explored the hypothesis that increased seizure susceptibility during early …

We have determined whether seizures generate an epileptogenic focus in distal structures
using an in vitro preparation composed of three independent chambers that accommodate …

GABA and glutamate receptors are expressed in immature "silent" CA1 pyramidal neurons
prior to synapse formation, but their function is unknown. We now report the presence of tonic, …

Morphological studies suggest that the primate hippocampus develops extensively before
birth, but little is known about its functional development. Patch-clamp recordings of …