[HTML][HTML] NAD+ repletion with niacin counteracts cancer cachexia

M Beltrà, N Pöllänen, C Fornelli, K Tonttila… - Nature …, 2023 - nature.com
Cachexia is a debilitating wasting syndrome and highly prevalent comorbidity in cancer
patients. It manifests especially with energy and mitochondrial metabolism aberrations that …

Oroboros O2k high-resolution respirometry for frozen samples and the effects of combined induction of muscle growth and angiogenesis on skeletal muscle …

K Tonttila - 2021 - helda.helsinki.fi
Respirometry is a polarographic method that provides insights into mitochondrial respiratory
capacity–specifically to electron transport chain (ETC) complexes I to V–, mitochondrial …

Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

HAK Lapatto, M Kuusela, A Heikkinen, M Muniandy… - Science …, 2023 - science.org
Nicotinamide adenine dinucleotide (NAD + ) precursor nicotinamide riboside (NR) has emerged
as a promising compound to improve obesity-associated mitochondrial dysfunction and …

[PDF][PDF] ISCaM2022ABSTRACT BOOK

PE Porporato - researchgate.net
The current targeted treatment for lung cancer patients harbouring BRAFV600E consists of
a dual blockade of RAF and MEK kinases often combining dabrafenib with trametinib (…