The quality of fetal growth and development predicts the risk for a range of noncommunicable,
chronic illnesses. These observations form the basis of the “developmental origins of …

BACKGROUND: Raised maternal anxiety during pregnancy is associated with increased
risk of adverse neurodevelopmental outcomes for her child. The mechanisms underlying this …

Developmental or fetal programming has emerged as a major model for understanding the
early and persisting effects of prenatal exposures on the health and development of the child …

We review studies with human and nonhuman species that examine the hypothesis that
epigenetic mechanisms, particularly those affecting the expression of genes implicated in stress …

There is clear evidence that the mother's stress, anxiety, or depression during pregnancy
can alter the development of her fetus and her child, with an increased risk for later …

Biological embedding occurs when life experience alters biological processes to affect later
life health and well-being. Although extensive correlative data exist supporting the notion …

Background Experimental animal work shows that prenatal stress has a persisting effect on
the hypothalamic-pituitary-adrenal (HPA) axis of offspring. The implications of these findings …

… Author links open overlay panel Christoph Anacker a b e , Jan Scholz f , Kieran J. O’Donnell
a , Rylan Allemang-Grand f , Josie Diorio a , Rosemary C. Bagot g h , Eric J. Nestler g h , …

The development of biological markers of aging has primarily focused on adult samples.
Epigenetic clocks are a promising tool for measuring biological age that show impressive …

Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms
allowing integration of genetic and environmental factors to shape cellular function. While many …