Age-related hearing loss (ARHL) negatively impacts quality of life in the elderly population.
The prevalent cause of ARHL is loss of mechanosensitive cochlear hair cells (HCs). The …

The mammalian auditory sensory epithelium, the organ of Corti, is composed of hair cells
and supporting cells. Hair cells contain specializations in the apical, basolateral and synaptic …

Inner hair cells (IHCs) and outer hair cells (OHCs) are the two anatomically and functionally
distinct types of mechanosensitive receptor cells in the mammalian cochlea. The molecular …

Although hair cells are the sensory receptors of the auditory and vestibular systems in the
ears of all vertebrates, hair cell properties are different between non-mammalian vertebrates …

Lysosomes contribute to cellular homeostasis via processes including macromolecule
degradation, nutrient sensing, and autophagy. Defective proteins related to lysosomal …

Non-mammalian vertebrates, including zebrafish, retain the ability to regenerate hair cells (HCs)
due to unknown molecular mechanisms that regulate proliferation and conversion of …

Hearing loss affects ∼10% of adults worldwide. Most sensorineural hearing loss is caused
by the progressive loss of mechanosensitive hair cells (HCs) in the cochlea. The molecular …

Simulation-based education (SBE) is common in healthcare education and is increasingly
being incorporated in preclinical curriculum. Preclinical students typically have had little …

Acquired hearing loss is a major health problem that affects 5-10% of the world population.
However, there are no FDA-approved drugs for the treatment or prevention of hearing loss. …

Hearing loss affects ~10% of adults worldwide and is irreversible. Most sensorineural hearing
loss is caused by progressive loss of mechanosensitive hair cells (HCs) in the cochlea of …