Background The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global,
community-driven effort to evaluate and improve the computational annotation of protein …

Cross-experiment comparisons in public data compendia are challenged by unmatched
conditions and technical noise. The ADAGE method, which performs unsupervised integration …

What are bacteria doing during “reversible attachment,” the period of transient surface
attachment when they initially engage a surface, besides attaching themselves to the surface? …

Pseudomonas aeruginosa is the most prevalent opportunistic pathogen in the airways of
cystic fibrosis (CF) patients. The pulmonary disorder is characterized by recurrent microbial …

The downregulation of Pseudomonas aeruginosa flagellar motility is a key event in biofilm
formation, host colonization, and the formation of microbial communities, but the external …

Mature neutrophils are notoriously short‐lived immune cells that cannot be genetically
manipulated. Analysis of gene function therefore requires genetically modified animals, which is …

Pseudomonas aeruginosa frequently encounters microbes that produce ethanol. Low
concentrations of ethanol reduced P. aeruginosa swim zone area by up to 45% in soft agar. The …

Mortality is a well-established patient-important outcome in critical care studies. In contrast,
morbidity is less uniformly reported (given the myriad of critical care illnesses and …

It is now known that there exist multifactorial influences on swarming motility for P. aeruginosa
, but it is not clear precisely why stator selection in the flagellum motor is so important. We …

Glycogen synthase kinase-3 (GSK3) is a highly conserved protein kinase that is involved in
several important cell signaling pathways and is associated with a range of medical …