MAIT cell activation and dynamics associated with COVID-19 disease severity

T Parrot, JB Gorin, A Ponzetta, KT Maleki… - Science …, 2020 - science.org
Severe COVID-19 is characterized by excessive inflammation of the lower airways. The
balance of protective versus pathological immune responses in COVID-19 is incompletely …

[HTML][HTML] Expansion of SARS-CoV-2–specific antibody-secreting cells and generation of neutralizing antibodies in hospitalized COVID-19 patients

R Varnaitė, M García, H Glans, KT Maleki… - The Journal of …, 2020 - journals.aai.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), emerged in late 2019 and has since become a global pandemic. …

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19

…, K Moll, M García, KT Maleki… - Proceedings of the …, 2021 - National Acad Sciences
Since the outset of the COVID-19 pandemic, increasing evidence suggests that the innate
immune responses play an important role in the disease development. A dysregulated …

Innate lymphoid cell composition associates with COVID‐19 disease severity

…, T Parrot, LM Palma Medina, KT Maleki… - Clinical & …, 2020 - Wiley Online Library
Objectives The role of innate lymphoid cells (ILCs) in coronavirus disease 2019 (COVID‐19),
caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is unknown. …

SARS‐CoV‐2‐specific humoral and cellular immunity persists through 9 months irrespective of COVID‐19 severity at hospitalisation

…, W Christ, P Chen, JR Muvva, KT Maleki… - Clinical & …, 2021 - Wiley Online Library
Objectives Humoral and cellular immunity to SARS‐CoV‐2 following COVID‐19 will likely
contribute to protection from reinfection or severe disease. It is therefore important to …

[HTML][HTML] Evaluation of 11 SARS-CoV-2 antibody tests by using samples from patients with defined IgG antibody titers

N Lagerqvist, KT Maleki, J Verner-Carlsson… - Scientific reports, 2021 - nature.com
We evaluated the performance of 11 SARS-CoV-2 antibody tests using a reference set of
heat-inactivated samples from 278 unexposed persons and 258 COVID-19 patients, some of …

Soluble SEMA4D/CD100: a novel immunoregulator in infectious and inflammatory diseases

KT Maleki, M Cornillet, NK Björkström - Clinical Immunology, 2016 - Elsevier
SEMA4D/CD100 is a homodimeric protein belonging to the semaphorin family of axonal
guidance proteins. Semaphorin family members have received increased attention lately due to …

Systematic evaluation of SARS‐CoV‐2 antigens enables a highly specific and sensitive multiplex serological COVID‐19 assay

…, Y Lindroth, M Lundgren, KT Maleki… - Clinical & …, 2021 - Wiley Online Library
Objective The COVID‐19 pandemic poses an immense need for accurate, sensitive and
high‐throughput clinical tests, and serological assays are needed for both overarching …

[HTML][HTML] Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia

…, H Babačić, M Dzidic, Å Parke, M Garcia, KT Maleki… - Respiratory …, 2023 - Springer
Background COVID-19 remains a major public health challenge, requiring the development
of tools to improve diagnosis and inform therapeutic decisions. As dysregulated …

Serum markers associated with severity and outcome of hantavirus pulmonary syndrome

KT Maleki, M García, A Iglesias, D Alonso… - The Journal of …, 2019 - academic.oup.com
Background Hantavirus pulmonary syndrome (HPS) is caused by Andes virus (ANDV) and
related hantaviruses in the Americas. Despite a fatality rate of 40%, the pathogenesis of HPS …