Eomesodermin promotes the development of type 1 regulatory T (TR1) cells

…, M Koyama, RD Kuns, KR Locke, KJ Beckett… - Science …, 2017 - science.org
Type 1 regulatory T (T R 1) cells are Foxp3 − interleukin-10 (IL-10)–producing CD4 + T cells
with potent immunosuppressive properties, but their requirements for lineage development …

[HTML][HTML] Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice

V Dasari, LK McNeil, K Beckett, M Solomon… - Nature …, 2023 - nature.com
The recent emergence of a causal link between Epstein-Barr virus (EBV) and multiple sclerosis
has generated considerable interest in the development of an effective vaccine against …

[HTML][HTML] EphA2 is a therapy target in EphA2-positive leukemias but is not essential for normal hematopoiesis or leukemia

S Charmsaz, K Beckett, FM Smith, C Bruedigam… - PloS one, 2015 - journals.plos.org
Members of the Eph family of receptor tyrosine kinases and their membrane bound ephrin
ligands have been shown to play critical roles in many developmental processes and more …

[HTML][HTML] A bivalent CMV vaccine formulated with human compatible TLR9 agonist CpG1018 elicits potent cellular and humoral immunity in HLA expressing mice

V Dasari, K Beckett, S Horsefield… - PLoS …, 2022 - journals.plos.org
There is now convincing evidence that the successful development of an effective CMV vaccine
will require improved formulation and adjuvant selection that is capable of inducing both …

A Lymph Node Targeted Adjuvant and Engineered Subunit Vaccine Promotes Potent Immunity to Epstein-Barr Virus in HLA-expressing Mice

V Dasari, L McNeil, K Beckett, M Solomon… - 2022 - researchsquare.com
Recent emergence of a causal like between Epstein-Barr virus (EBV) and multiple sclerosis
has generated considerable interest in the development of an effective vaccine against EBV. …

Antibody binding to native cytomegalovirus glycoprotein B predicts efficacy of the gB/MF59 vaccine in humans

JA Jenks, CS Nelson, HK Roark, ML Goodwin… - Science translational …, 2020 - science.org
Human cytomegalovirus (CMV) is the most common infectious cause of infant brain damage
and posttransplant complications worldwide. Despite the high global burden of disease, …