User profiles for Kirsten Gotting

Kirsten Gotting

Postdoctoral Researcher at Harvard University
Verified email at g.harvard.edu
Cited by 530

Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates

W Wang, CK Hu, A Zeng, D Alegre, D Hu, K Gotting… - Science, 2020 - science.org
INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate a …

SmedGD 2.0: The Schmidtea mediterranea genome database

SMC Robb, K Gotting, E Ross, A Sánchez Alvarado - genesis, 2015 - Wiley Online Library
Planarians have emerged as excellent models for the study of key biological processes such
as stem cell function and regulation, axial polarity specification, regeneration, and tissue …

[PDF][PDF] Egf signaling directs neoblast repopulation by regulating asymmetric cell division in planarians

…, SA McKinney, CW Seidel, R Alexander, K Gotting… - Developmental cell, 2016 - cell.com
A large population of proliferative stem cells (neoblasts) is required for physiological tissue
homeostasis and post-injury regeneration in planarians. Recent studies indicate that survival …

Embryonic origin of adult stem cells required for tissue homeostasis and regeneration

…, SA McKinney, L Guo, SMC Robb, EJ Ross, K Gotting… - Elife, 2017 - elifesciences.org
10.7554/eLife.21052.001 Planarian neoblasts are pluripotent, adult somatic stem cells and
lineage-primed progenitors that are required for the production and maintenance of all …

Genomic diversification of the specialized parasite of the fungus-growing ant symbiosis

K Gotting, DS May, J Sosa-Calvo… - Proceedings of the …, 2022 - National Acad Sciences
Fungi shape the diversity of life. Characterizing the evolution of fungi is critical to understanding
symbiotic associations across kingdoms. In this study, we investigate the genomic and …

Head regeneration in hemichordates is not a strict recapitulation of development

SM Luttrell, K Gotting, E Ross… - Developmental …, 2016 - Wiley Online Library
Background: Head or anterior body part regeneration is commonly associated with
protostome, but not deuterostome invertebrates. However, it has been shown that the solitary …

Bacteria contribute to plant secondary compound degradation in a generalist herbivore system

…, L Khadempour, RD Moreira-Soto, K Gotting… - MBio, 2020 - Am Soc Microbiol
Herbivores must overcome a variety of plant defenses, including coping with plant secondary
compounds (PSCs). To help detoxify these defensive chemicals, several insect herbivores …

Selection and Characterization of Mutants Defective in DNA Methylation in Neurospora crassa

…, WK Storck, KJ McNaught, ND Moss, K Gotting… - Genetics, 2020 - academic.oup.com
DNA methylation, a prototypical epigenetic modification implicated in gene silencing, occurs
in many eukaryotes and plays a significant role in the etiology of diseases such as cancer. …

A nuclear hormone receptor and lipid metabolism axis are required for the maintenance and regeneration of reproductive organs

…, L Guo, C Guerrero-Hernández, EJ Ross, K Gotting… - bioRxiv, 2018 - biorxiv.org
Understanding how stem cells and their progeny maintain and regenerate reproductive
organs is of fundamental importance. The freshwater planarian Schmidtea mediterranea …

[BOOK][B] The Evolution and Ecology of Fungal Symbionts in Ant-associated Mutualisms

K Gotting - 2023 - search.proquest.com
… symbionts in ant-associated mutualisms by Kirsten Leigh Gotting A dissertation submitted
in … and ecology of fungal symbionts in ant-associated mutualisms By Kirsten Leigh Gotting