User profiles for Kirstine Calloe
 | Kirstine CalloeUniversity of Copenhagen Verified email at sund.ku.dk Cited by 2286 |
[HTML][HTML] Managing the complexity of communication: regulation of gap junctions by post-translational modification
Gap junctions are comprised of connexins that form cell-to-cell channels which couple
neighboring cells to accommodate the exchange of information. The need for communication does…
neighboring cells to accommodate the exchange of information. The need for communication does…
The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels
BH Bentzen, A Nardi, K Calloe, LS Madsen… - Molecular …, 2007 - ASPET
Large-conductance Ca 2+ - and voltage-activated K + channels (Kca1.1/BK/MaxiK) are widely
expressed ion channels. They provide a Ca 2+ -dependent feedback mechanism for the …
expressed ion channels. They provide a Ca 2+ -dependent feedback mechanism for the …
A novel KCND3 gain-of-function mutation associated with early-onset of persistent lone atrial fibrillation
Aims Atrial fibrillation (AF) is the most common cardiac arrhythmia, and early-onset lone AF
has been linked to mutations in genes encoding ion channels. Mutations in the pore forming …
has been linked to mutations in genes encoding ion channels. Mutations in the pore forming …
Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome
JM Cordeiro, M Marieb, R Pfeiffer, K Calloe… - Journal of molecular and …, 2009 - Elsevier
Recent studies have demonstrated an association between mutations in CACNA1c or
CACNB2b and Brugada syndrome (BrS). Previously described mutations all caused a loss of …
CACNB2b and Brugada syndrome (BrS). Previously described mutations all caused a loss of …
A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome
Aims Transient outward potassium current (I to ) is thought to be central to the pathogenesis
of the Brugada syndrome (BrS). However, an I to activator has not been available with which …
of the Brugada syndrome (BrS). However, an I to activator has not been available with which …
[HTML][HTML] Structure of the human ClC-1 chloride channel
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes,
thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with …
thereby orchestrating skeletal muscle excitability. Malfunction of ClC-1 is associated with …
The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels
The family of Kv7 (KCNQ) potassium channels consists of five members. Kv7.2 and 3 are
the primary molecular correlates of the M-current, but also Kv7.4 and Kv7.5 display M-current …
the primary molecular correlates of the M-current, but also Kv7.4 and Kv7.5 display M-current …
[PDF][PDF] Patient iPSC-derived neurons for disease modeling of frontotemporal dementia with mutation in CHMP2B
The truncated mutant form of the charged multivesicular body protein 2B (CHMP2B) is causative
for frontotemporal dementia linked to chromosome 3 (FTD3). CHMP2B is a constituent …
for frontotemporal dementia linked to chromosome 3 (FTD3). CHMP2B is a constituent …
[HTML][HTML] Quantitative proteome comparison of human hearts with those of model organisms
Delineating human cardiac pathologies and their basic molecular mechanisms relies on
research conducted in model organisms. Yet translating findings from preclinical models to …
research conducted in model organisms. Yet translating findings from preclinical models to …
[HTML][HTML] Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
Background Type 2 diabetes is associated with abnormal electrical conduction and sudden
cardiac death, but the pathogenic mechanism remains unknown. This study describes …
cardiac death, but the pathogenic mechanism remains unknown. This study describes …