Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …

Background— The optimal stenting strategy in coronary artery bifurcation lesions is unknown.
In the present study, a strategy of stenting both the main vessel and the side branch (MV+…

Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex
heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (…

Blood cells play essential roles in human health, underpinning physiological processes
such as immunity, oxygen transport, and clotting, which when perturbed cause a significant …

Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …

We carried out a trans-ancestry genome-wide association and replication study of blood
pressure phenotypes among up to 320,251 individuals of East Asian, European and South …

Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death 1 , 2 . Fourteen genetic loci have been associated with atrial …

Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via poorly
understood mechanisms. We performed a trans-ancestry genome-wide association study …

Objectives : This study sought to report the 5-year follow-up results of the Nordic Bifurcation
Study. Background : Randomized clinical trials with short-term follow-up have indicated that …

Background— In a number of coronary bifurcation lesions, both the main vessel and the
side branch need stent coverage. Using sirolimus eluting stents, we compared 2 dedicated …