Efficacy of HIV postexposure prophylaxis: systematic review and meta-analysis of nonhuman primate studies
…, KJ Egan, Z Shubber, KKA Van Rompay… - Clinical Infectious …, 2015 - academic.oup.com
Background. The efficacy of antiretrovirals as postexposure prophylaxis (PEP) to prevent viral
acquisition was demonstrated in nonhuman primate models of human immunodeficiency …
acquisition was demonstrated in nonhuman primate models of human immunodeficiency …
[HTML][HTML] An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar
…, DE Brackney, S Grewal, N Gurfield, KKA Van Rompay… - Genome biology, 2019 - Springer
How viruses evolve within hosts can dictate infection outcomes; however, reconstructing
this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …
this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …
The use of nonhuman primate models of HIV infection for the evaluation of antiviral strategies
KKA Van Rompay - AIDS research and human retroviruses, 2012 - liebertpub.com
… 20 Van Rompay KKEvaluation of antiretrovirals in animal models of HIV infectionAntiviral
Res201085159175. 20. Van Rompay KK: Evaluation of antiretrovirals in animal models of HIV …
Res201085159175. 20. Van Rompay KK: Evaluation of antiretrovirals in animal models of HIV …
Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems
…, D Lu, M Rauch, Y Huang, KKA Van Rompay… - Science translational …, 2014 - science.org
Diet has a strong influence on the intestinal microbiota in both humans and animal models.
It is well established that microbial colonization is required for normal development of the …
It is well established that microbial colonization is required for normal development of the …
[HTML][HTML] SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques
…, MP Busch, PA Kozlowski, KKA Van Rompay… - Nature …, 2021 - nature.com
CD4 T follicular helper (T fh ) cells are important for the generation of durable and specific
humoral protection against viral infections. The degree to which SARS-CoV-2 infection …
humoral protection against viral infections. The degree to which SARS-CoV-2 infection …
Evaluation of antiretrovirals in animal models of HIV infection
KKA Van Rompay - Antiviral research, 2010 - Elsevier
Animal models of HIV infection have played an important role in the development of
antiretroviral drugs. Although each animal model has its limitations and never completely mimics …
antiretroviral drugs. Although each animal model has its limitations and never completely mimics …
Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological …
KKA Van Rompay, L Durand-Gasselin… - Antimicrobial agents …, 2008 - Am Soc Microbiol
The reverse transcriptase (RT) inhibitor tenofovir (TFV) is highly effective in the simian
immunodeficiency virus (SIV) macaque model of human immunodeficiency virus infection. The …
immunodeficiency virus (SIV) macaque model of human immunodeficiency virus infection. The …
Passive immunization of newborn rhesus macaques prevents oral simian immunodeficiency virus infection
KKA Van Rompay, CJ Berardi… - The Journal of …, 1998 - academic.oup.com
To determine if passively acquired antiviral antibodies modulate virus transmission and
disease progression in human pediatric AIDS, the potential of pre- and postexposure passive …
disease progression in human pediatric AIDS, the potential of pre- and postexposure passive …
Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy) propyl] adenine (tenofovir) to newborn and infant rhesus macaques
KKA Van Rompay, LL Brignolo, DJ Meyer… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir)
was previously found to offer strong prophylactic and therapeutic benefits in an infant …
was previously found to offer strong prophylactic and therapeutic benefits in an infant …
[PDF][PDF] SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
…, BA Schmidt, RL Sammak, KKA Van Rompay… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 2019 (COVID-19), can induce a plethora of neurological complications in …
coronavirus disease 2019 (COVID-19), can induce a plethora of neurological complications in …