User profiles for Kolea Zimmerman

Kolea Zimmerman

Associate Technical Director - Microbial Engineering, Ginkgo Bioworks
Verified email at ginkgobioworks.com
Cited by 36

Is meiosis a fundamental cause of inviability among sexual and asexual plants and animals?

DA Levitis, K Zimmerman… - Proceedings of the …, 2017 - royalsocietypublishing.org
Differences in viability between asexually and sexually generated offspring strongly
influence the selective advantage and therefore the prevalence of sexual reproduction (sex). …

Fungal seed pathogens of wild chili peppers possess multiple mechanisms to tolerate capsaicinoids

CA Adams, K Zimmerman… - Applied and …, 2020 - Am Soc Microbiol
The wild chili pepper Capsicum chacoense produces the spicy defense compounds known
as capsaicinoids, including capsaicin and dihydrocapsaicin, which are antagonistic to the …

Beyond animals and plants: dynamic maternal effects in the fungus Neurospora crassa

KCK Zimmerman, DA Levitis… - Journal of evolutionary …, 2016 - academic.oup.com
Maternal effects are widely documented in animals and plants, but not in fungi or other
eukaryotes. A principal cause of maternal effects is asymmetrical parental investment in a zygote, …

[HTML][HTML] Selection of pairings reaching evenly across the data (SPREAD): A simple algorithm to design maximally informative fully crossed mating experiments

K Zimmerman, D Levitis, E Addicott, A Pringle - Heredity, 2016 - nature.com
We present a novel algorithm for the design of crossing experiments. The algorithm
identifies a set of individuals (a ‘crossing-set’) from a larger pool of potential crossing-sets by …

Development of an engineered probiotic for the treatment of branched chain amino acid related metabolic diseases

…, R Jain, R Putman, S Marr, D Carlin, K Zimmerman… - 2021 - researchsquare.com
Metabolic dysfunction arising from missing or impaired enzymes comprising the branched
chain amino acid (BCAA) degradation pathway, especially those involving leucine, can result …

The Genetics of Life History Traits in the Fungus Neurospora crassa

K Zimmerman - 2016 - dash.harvard.edu
The study of life histories is fundamental to understanding why some organisms live for a very
short time while others live for a long time, why some produce thousands of offspring while …

Fungal endophyte communities reflect environmental structuring across a Hawaiian landscape

NB Zimmerman, PM Vitousek - Proceedings of the National …, 2012 - National Acad Sciences
We surveyed endophytic fungal communities in leaves of a single tree species (Metrosideros
polymorpha) across wide environmental gradients (500–5,500 mm of rain/y; 10–22 C …

Maternal parentage influences spore production but not spore pigmentation in the anisogamous and hermaphroditic fungus Neurospora crassa

K Zimmerman, D Levitis, A Pringle - 2014 - portal.findresearcher.sdu.dk
In this study, we tested the hypothesis that maternal effects on offspring production and quality
are greater than paternal effects in both offspring number (fertility) and offspring viability (…

Meiotic faults as a major cause of offspring inviability: Comparative evidence and implications for the evolution of sex

D Levitis, K Zimmerman, A Pringle - 2014 - portal.findresearcher.sdu.dk
The extensive literature on the costs and benefits of sexual reproduction often concludes
that increased offspring viability is a benefit of sexual reproduction as compared to …

Populations and individuals in heterokaryotic fungi: a multilevel perspective

A Booth - Philosophy of Science, 2014 - cambridge.org
Among mycologists, questions persist about what entities should be treated as the fundamental
units of fungal populations. This article articulates a coherent view about populations of …