The adult immune system consists of cells that emerged at various times during ontogeny.
We aimed to define the relationship between developmental origin and composition of the …

Initiation of adaptive immunity to particulate antigens in lymph nodes largely depends on
their presentation by migratory dendritic cells (DCs). DC subsets differ in their capacity to …

Lymphoid organ hypertrophy is a characteristic feature of acute infection and is considered
to enable efficient induction of adaptive immune responses. Accordingly, oral infection with …

Rotavirus (RV) infection induces strong adaptive immunity. While protection from reinfection
requires humoral immunity, initial clearance of infection depends on cytotoxic CD8 T cells. …

Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the
age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year …

Initiation of adaptive immunity to particulate antigens in lymph nodes largely depends on
their presentation by migratory dendritic cells (DCs). DC subsets differ in their capacity to …

… Getachew, thanks for the nice discussions about our country, Ethiopia. I think I missed
that since you left the lab. Isabel, thanks for the fruitful collaboration and fun times. …

Activators of innate immunity may have the potential to combat a broad range of infectious
agents. We report that treatment with bacterial flagellin prevented rotavirus (RV) infection in …

The intestine is continuously challenged to generate protective immunity against harmful
antigens, such as pathogens, and tolerance against harmless materials, such as food. Dendritic …

Redundant mechanisms support immunoglobulin A (IgA) responses to intestinal antigens.
These include multiple priming sites [mesenteric lymph nodes (MLNs), Peyer’s patches, and …