User profiles for Konrad L. M. Rudolph

Konrad LM Rudolph

F. Hoffman-La Roche AG
Verified email at roche.com
Cited by 609

[HTML][HTML] Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

…, PL Germain, W Matsushima, KLM Rudolph… - Molecular …, 2020 - nature.com
Psychiatric diseases have a strong heritable component known to not be restricted to DNA
sequence-based genetic inheritance alone but to also involve epigenetic factors in germ cells…

High-resolution mapping of transcriptional dynamics across tissue development reveals a stable mRNA–tRNA interface

BM Schmitt, KLM Rudolph, P Karagianni… - Genome …, 2014 - genome.cshlp.org
The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly
interact during protein synthesis; the stability and regulation of this interaction remains …

[HTML][HTML] Codon-driven translational efficiency is stable across diverse mammalian cell states

KLM Rudolph, BM Schmitt, D Villar, RJ White… - PLoS …, 2016 - journals.plos.org
Whether codon usage fine-tunes mRNA translation in mammals remains controversial, with
recent papers suggesting that production of proteins in specific Gene Ontological (GO) …

Terminal uridylyltransferases target RNA viruses as part of the innate immune system

…, C Leung, M Morgan, C Much, KLM Rudolph… - Nature structural & …, 2018 - nature.com
RNA viruses are a major threat to animals and plants. RNA interference (RNAi) and the
interferon response provide innate antiviral defense against RNA viruses. Here, we performed a …

[PDF][PDF] The helicase aquarius/EMB-4 is required to overcome intronic barriers to allow nuclear RNAi pathways to heritably silence transcription

…, AC Berkyurek, X Zhang, CJ Wedeles, KLM Rudolph… - Developmental cell, 2017 - cell.com
Small RNAs play a crucial role in genome defense against transposable elements and guide
Argonaute proteins to nascent RNA transcripts to induce co-transcriptional gene silencing. …

The profile and dynamics of RNA modifications in animals

…, A Akay, SM Huber, C Bueschl, KLM Rudolph… - …, 2017 - Wiley Online Library
More than a hundred distinct modified nucleosides have been identified in RNA, but little is
known about their distribution across different organisms, their dynamic nature and their …

Terminal uridylyltransferases target RNA viruses as part of the innate immune system in animals

…, J Kosałka, M Morgan, C Much, KLM Rudolph… - bioRxiv, 2017 - biorxiv.org
RNA viruses are a major threat to animals and plants. RNA interference (RNAi) and the
interferon response provide innate antiviral defense against RNA viruses. Here we performed a …

A phase I study of recombinant interleukin 2 plus recombinant β-interferon

…, KA Padavic-Shaller, AR Rudolph, S Litwin, M Konrad… - Cancer research, 1988 - AACR
Interleukin 2 (IL-2) therapies have antitumor activities against several neoplasms. In vitro these
activities are enhanced by β-interferon (IFN-β). Therefore, we initiated a Phase I trial with …

Properties of unbound high-spin states in27Al

…, P Konrad, KEG Löbner, U Quade, K Rudolph… - Zeitschrift für Physik A …, 1984 - Springer
Selectively excited high-spin states in 27 Al have been located by the reaction 12 C( 16 O,p)
27 Al. The excitation functions of these states have been measured at incident energiesE …

Obituary notices: Friedrich Konrad Beilstein, 1838–1906; Emil Erlenmeyer, 1825–1909; Rudolph Fittig, 1835–1910; Hans Heinrich Landolt, 1831–1910; Nikolai …

ON Witt - Journal of the Chemical Society, Transactions, 1911 - pubs.rsc.org
THE honorary membership of the great learned societies is a testimony of admiration for the
brilliant work done by its recipients. In the case of Beilstein it was more; it was, above all, an …