Single-molecule spatial transcriptomics protocols based on in situ sequencing or
multiplexed RNA fluorescent hybridization can reveal detailed tissue organization. However, …

Adult intestinal stem cells are located at the bottom of crypts of Lieberkühn, where they
express markers such as LGR5 1 , 2 and fuel the constant replenishment of the intestinal …

To understand the function of cortical circuits, it is necessary to catalog their cellular diversity.
Past attempts to do so using anatomical, physiological or molecular features of cortical …

Schizophrenia is one of the most widespread and complex mental disorders. To
characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing (snRNA-seq) …

Single-cell RNA sequencing is often applied in study designs that include multiple individuals,
conditions or tissues. To identify recurrent cell subpopulations in such heterogeneous …

Epilepsy is one of the most common neurological disorders, yet its pathophysiology is
poorly understood due to the high complexity of affected neuronal circuits. To identify …

Neurogenic regions of mammalian brain produce many more neurons that will eventually
survive and reach a mature stage. Developmental cell death affects both embryonically …

The subventricular zone (SVZ) of the lateral ventricles is the largest neurogenic niche of the
postnatal brain. New SVZ-generated neurons migrate via the rostral migratory stream to the …

In adult rodents stroke enhances neurogenesis resulting in the addition of neurons to
forebrain regions such as striatum or cortex where postnatal neurogenesis under normal …

Neurodevelopmental disorders arise due to various risk factors that can perturb different
stages of brain development, and a combinatorial impact of these risk factors programs the …