Tissue resident mast cells (MCs) rapidly initiate neutrophil infiltration upon inflammatory
insult, yet the molecular mechanism is still unknown. Here, we demonstrated that MC-derived …

Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However, …

Although mast cells (MCs) are known as key drivers of type I allergic reactions, there is
increasing evidence for their critical role in host defense. MCs not only play an important role in …

The NF-κB/Rel signalling pathway plays a crucial role in numerous biological processes,
including innate and adaptive immunity. NF-κB is a family of transcription factors, whose activity …

By studying hapten-induced contact hypersensitivity (CHS) responses in novel transgenic
mouse lines of MC deficiency or conditional gene knockout, we have previously demonstrated …

Mast cells may contribute to osteoporosis development, because patients with age-related
or post-menopausal osteoporosis exhibit more mast cells in the bone marrow, and …

… Konstantinos Katsoulis-Dimitriou was supported … Konstantinos Katsoulis-Dimitriou carried
out the experiments and wrote the manuscript. Sarah Frentzel, Konstantinos Katsoulis-Dimitriou…

Staphylococcus aureus can lead to chronic infections and abscesses in internal organs
including kidneys, which are associated with the expansion of myeloid-derived suppressor cells (…

Staphylococcus aureus is considered a dangerous pathogen due to its ability to evade the
immune system and resist multiple antibiotics. These evasive strategies lead to difficult-to-…

1. Abstract The NF-κB transcription pathway is extremely important for immune responses
and homeostasis. Therefore, strong regulation of it is absolutely necessary. One of these …