Nicotinamide adenine dinucleotide (NAD + ) is modulated by conditions of metabolic stress
and has been reported to decline with aging in preclinical models, but human data are …

Upper- and lower-body fat depots exhibit opposing associations with obesity-related metabolic
disease. We defined the relationship between DEXA-quantified fat depots and diabetes/…

Background Androgen excess is a defining feature of polycystic ovary syndrome (PCOS),
which affects 10% of women and represents a lifelong metabolic disorder, with increased risk …

Background: Benign adrenal tumors are commonly discovered on cross-sectional imaging.
Mild autonomous cortisol secretion (MACS) is regularly diagnosed, but its effect on …

Context Polycystic ovary syndrome (PCOS) is a prevalent metabolic disorder occurring in
up to 10% of women of reproductive age. PCOS is associated with insulin resistance and …

Obesity is a complex disorder of excessive adiposity, and is associated with adverse health
effects such as cardiometabolic complications, which are to a large extent attributable to …

Introduction Upper and lower body fat accumulation poses an opposing obesity-related
cardiometabolic disease risk. Depot-differences in subcutaneous adipose tissue (SAT) function …

Introduction Brown adipose tissue (BAT) is a thermogenic organ with substantial metabolic
capacity and has important roles in the maintenance of body weight and metabolism. …

Objective Previous studies suggest that androgens have a sexually dimorphic impact on
metabolic dysfunction. However, the sex‐specific link between circulating androgens and risk of …

Polycystic ovary syndrome (PCOS) has been traditionally perceived as a reproductive disorder
due to its most common presentation with menstrual dysfunction and infertility. However, …