The nuclear pore complex (NPC) is the principal gateway for transport into and out of the
nucleus. Selectivity is achieved through the hydrogel-like core of the NPC. The structural …

… dedicated to Kotaro Kelley and his family to serve as a memory of him. Kotaro conceived of
… Kotaro conceived of the Waffle Method as a specific solution to several collaborative projects…

Cryo-electron microscopy (cryoEM) is becoming the preferred method for resolving protein
structures. Low signal-to-noise ratio (SNR) in cryoEM images reduces the confidence and …

Alkylgold(I) complexes were formed from the gold(I)-promoted intramolecular addition of
various amine nucleophiles to alkenes. These experiments provide the first direct experimental …

Given an image dataset, we are often interested in finding data generative factors that
encode semantic content independently from pose variables such as rotation and translation. …

Thyroglobulin is a homodimeric glycoprotein that is essential for the generation of thyroid
hormones in vertebrates. Upon secretion into the lumen of follicles in the thyroid gland, tyrosine …

Recent advances in instrumentation and software for cryoEM have increased the applicability
and utility of this method. High levels of automation and faster data acquisition rates …

… dedicated to Kotaro Kelley and his family, and serves as a memory of him. Kotaro conceived
… Kotaro conceived of the Waffle Method as a specific solution to several collaborative projects…

Recent advances in instrumentation and software for cryoEM have increased the applicability
and utility of this method. Coupled with the adoption of automated pipelines, significant …

Cryo-electron tomography (cryo-ET) allows researchers to directly observe proteins and
subcellular structures in their native 3D cellular contexts at nanometer and sub-nanometer …