User profiles for Kotoka Nakamura
 | Kotoka NakamuraCedars Sinai Medical Center Verified email at cshs.org Cited by 1995 |
[PDF][PDF] ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation
MA Kennedy, GC Barrera, K Nakamura, Á Baldán… - Cell metabolism, 2005 - cell.com
Here we demonstrate that the ABC transporter ABCG1 plays a critical role in lipid
homeostasis by controlling both tissue lipid levels and the efflux of cellular cholesterol to HDL. …
homeostasis by controlling both tissue lipid levels and the efflux of cellular cholesterol to HDL. …
[HTML][HTML] Expression and regulation of multiple murine ATP-binding cassette transporter G1 mRNAs/isoforms that stimulate cellular cholesterol efflux to high density …
K Nakamura, MA Kennedy, A Baldán… - Journal of Biological …, 2004 - ASBMB
The murine Abcg1 gene is reported to consist of 15 exons that encode a single mRNA (herein
referred to as Abcg1-a) and protein. We now demonstrate that (i) the murine gene …
referred to as Abcg1-a) and protein. We now demonstrate that (i) the murine gene …
Out-of-hospital cardiac arrest response and outcomes during the COVID-19 pandemic
…, HS Chugh, A Sargsyan, K Nakamura… - Clinical …, 2021 - jacc.org
Objectives The purpose of this study was to evaluate the potential impact of the coronavirus
disease-2019 (COVID-19) pandemic on out-of-hospital cardiac arrest (OHCA) responses …
disease-2019 (COVID-19) pandemic on out-of-hospital cardiac arrest (OHCA) responses …
[HTML][HTML] miR-34 activity is modulated through 5′-end phosphorylation in response to DNA damage
DW Salzman, K Nakamura, S Nallur… - Nature …, 2016 - nature.com
MicroRNA (miRNA) expression is tightly regulated by several mechanisms, including
transcription and cleavage of the miRNA precursor RNAs, to generate a mature miRNA, which is …
transcription and cleavage of the miRNA precursor RNAs, to generate a mature miRNA, which is …
[HTML][HTML] Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia
SS Devgan, O Sanal, C Doil, K Nakamura… - Cell Death & …, 2011 - nature.com
Maintaining genomic integrity is critical to avoid life-threatening disorders, such as premature
aging, neurodegeneration and cancer. A multiprotein cascade operates at sites of DNA …
aging, neurodegeneration and cancer. A multiprotein cascade operates at sites of DNA …
Evaluation of sudden cardiac arrest by race/ethnicity among residents of Ventura county, California, 2015-2020
…, A Sargsyan, HS Chugh, K Nakamura… - JAMA Network …, 2021 - jamanetwork.com
Importance Sudden cardiac arrest (SCA) is a major public health problem. Owing to a lack
of population-based studies in multiracial/multiethnic communities, little information is …
of population-based studies in multiracial/multiethnic communities, little information is …
Sudden cardiac arrest during the COVID-19 pandemic: A two-year prospective evaluation in a North American community
HS Chugh, A Sargsyan, K Nakamura, A Uy-Evanado… - Heart Rhythm, 2023 - Elsevier
Background Early during the coronavirus disease 2019 (COVID-19) pandemic, higher sudden
cardiac arrest (SCA) incidence and lower survival rates were reported. However, ongoing …
cardiac arrest (SCA) incidence and lower survival rates were reported. However, ongoing …
[HTML][HTML] Warning symptoms associated with imminent sudden cardiac arrest: a population-based case-control study with external validation
…, A Uy-Evanado, FL Norby, K Nakamura… - The Lancet Digital …, 2023 - thelancet.com
Background Sudden cardiac arrest is a global public health problem with a mortality rate of
more than 90%. Prearrest warning symptoms could be harnessed using digital technology to …
more than 90%. Prearrest warning symptoms could be harnessed using digital technology to …
[HTML][HTML] ATM–dependent miR-335 targets CtIP and modulates the DNA damage response
NT Martin, K Nakamura, R Davies, SA Nahas… - PLoS …, 2013 - journals.plos.org
ATM plays a critical role in cellular responses to DNA double-strand breaks (DSBs). We
describe a new ATM–mediated DSB–induced DNA damage response pathway involving …
describe a new ATM–mediated DSB–induced DNA damage response pathway involving …
Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia‐telangiectasia
K Nakamura, L Du, R Tunuguntla, F Fike… - Human …, 2012 - Wiley Online Library
A recent challenge for investigators studying the progressive neurological disease ataxia‐telangiectasia
(A‐T) is to identify mutations whose effects might be alleviated by mutation‐…
(A‐T) is to identify mutations whose effects might be alleviated by mutation‐…