Interleukin-25 (IL-25) and group 2 innate lymphoid cells (ILC2s) defend the host against
intestinal helminth infection and are associated with inappropriate allergic reactions. IL-33–…

Immediately prior to invasion Toxoplasma gondii tachyzoites release a large number of
micronemal proteins (TgMICs) that participate in host cell attachment and penetration. The …

Toxosplasma gondii is the model parasite of the phylum Apicomplexa, which contains numerous
obligate intracellular parasites of medical and veterinary importance, including Eimeria, …

Passive immunization using monoclonal antibodies will play a vital role in the fight against
COVID-19. The recent emergence of viral variants with reduced sensitivity to some current …

The precise spatiotemporal control of cell proliferation is key to the morphogenesis of
epithelial tissues. Epithelial cell divisions lead to tissue crowding and local changes in force …

Programmed death-ligand 1 (PD-L1) is a key immune regulatory protein that interacts with
programmed cell death protein 1 (PD-1), leading to T-cell suppression. Whilst this interaction …

Osteoporosis and multiple sclerosis are highly prevalent diseases with limited treatment
options. In light of these unmet medical needs, novel therapeutic approaches are urgently …

The obligate intracellular parasite Toxoplasma gondii, a member of the phylum Apicomplexa
that includes Plasmodium spp., is one of the most widespread parasites and the causative …

Microneme protein 4 is involved in cell binding by the important parasite Toxoplasma gondii.
We present here the backbone and side-chain assignments of the first two apple domains …

NOD2 activation by muramyl dipeptide causes a proinflammatory immune response in
which the adaptor protein CARD9 works synergistically with NOD2 to drive p38 and c-Jun N-…