[HTML][HTML] A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
…, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White… - Nature, 2020 - nature.com
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
which is the causative agent of coronavirus disease 2019 (COVID-19), has …
[HTML][HTML] Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
…, KY Sit, L Martinez-Sobrido, WC Liu, KM White… - Nature, 2020 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
has triggered an ongoing global pandemic of the severe pneumonia-like disease …
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
INTRODUCTION The emergence of three lethal coronaviruses in <20 years and the urgency
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …
of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, …
[PDF][PDF] The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White… - Cell, 2020 - cell.com
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed hundreds …
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus enters host cells
via an interaction between its Spike protein and the host cell receptor angiotensin-converting …
via an interaction between its Spike protein and the host cell receptor angiotensin-converting …
[HTML][HTML] Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
…, LW Updyke, S Weston, Y Zhu, KM White… - Nature …, 2021 - nature.com
COVID-19 caused by the SARS-CoV-2 virus has become a global pandemic. 3CL protease
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
is a virally encoded protein that is essential across a broad spectrum of coronaviruses with …
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins interact with
the eukaryotic translation machinery, and inhibitors of translation have potent antiviral effects. …
the eukaryotic translation machinery, and inhibitors of translation have potent antiviral effects. …
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
…, E Moreno, O Danziger, KM White… - Proceedings of the …, 2020 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health …
the ongoing coronavirus disease 2019 (COVID-19) pandemic that is a serious global health …
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
…, A Fischer, MJ O'meara, B Monel, T Vallet, KM White… - Science, 2021 - science.org
Repurposing drugs as treatments for COVID-19, the disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention. Beginning with …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has drawn much attention. Beginning with …
[PDF][PDF] Transcription elongation can affect genome 3D structure
…, MW Chang, N Givarkes, A Rialdi, KM White… - Cell, 2018 - cell.com
How transcription affects genome 3D organization is not well understood. We found that during
influenza A (IAV) infection, rampant transcription rapidly reorganizes host cell chromatin …
influenza A (IAV) infection, rampant transcription rapidly reorganizes host cell chromatin …