… where C int_larvae (t) is the chemical concentration in the whole larvae (amount × mass −1
), C int_eyes (t) is the chemical concentration in the larvae’s eyes (amount × mass −1 ), C …

The number of new psychoactive substances (NPS) on the illicit drug market increases fast,
posing a need to urgently understand their toxicity and behavioural effects. However, with …

A series of functionalized phenyl oxazole derivatives was designed, synthesized and screened
in vitro for their activities against LSD1 and for effects on viability of cervical and breast …

The analysis of larval zebrafish locomotor behavior has emerged as a powerful indicator of
perturbations in the nervous system and is used in many fields of research, including …

The number of new psychoactive substances (NPS) increases rapidly, harming society and
fuelling the need for alternative testing strategies. These should allow the ever-increasing …

Background and methods We describe a method for obtaining pharmacokinetics (PK) and
pharmacology data from adult zebrafish in terms of mg/kg using a novel method of oral …

… Krishna Tulasi Kirla: study design and concept, conducted the data analyses, assisted with
interpretation of the data, manuscript preparation. Szilárd Nemes: study design and concept, …

Abbreviation/symbol Units Value Description w_w kg model input body wet weight Kow―
model input octanol-water partition coefficient Cw µg· L-1 model input chemical concentration …

Exploring the role of toxicokinetics in the response of zebrafish embryos and larvae to chemical
exposure English Français login Menu Search Browse Collections Help English Français login …

Zebrafish larvae exposed to cocaine accumulate cocaine in the eye. Here we used
electroretinography (ERG) to assess the effect of accumulated cocaine on the outer retina function of …