Methods for culturing mammalian cells ex vivo are increasingly needed to study cell and
tissue physiology and to grow replacement tissue for regenerative medicine. Two‐dimensional …

We report a strategy to create photodegradable poly(ethylene glycol)–based hydrogels
through rapid polymerization of cytocompatible macromers for remote manipulation of gel …

We investigated whether stem cells remember past physical signals and whether these can
be exploited to dose cells mechanically. We found that the activation of the Yes-associated …

… Kristi S. Anseth [email protected] KS Anseth is in the Department of Chemical and Biological
Engineering and the Howard Hughes Medical Institute, University of Colorado, Boulder, CO …

The extracellular matrix (ECM) is a dynamic environment that constantly provides physical
and chemical cues to embedded cells. Much progress has been made in engineering …

Click chemistry provides extremely selective and orthogonal reactions that proceed with
high efficiency and under a variety of mild conditions, the most common example being the …

Hydrogels are increasingly employed as multidimensional cell culture platforms often with a
necessity that they respond to or control the cellular environment. Specifically, synthetic …

Thiol-ene photopolymerization offers a unique platform for the formation of peptide-functionalized
poly(ethylene glycol) hydrogels and the encapsulation, culture and differentiation of …

Microenvironment elasticity influences critical cell functions such as differentiation,
cytoskeletal organization, and process extension. Unfortunately, few materials allow elasticity …

The click reaction paradigm is focused on the development and implementation of reactions
that are simple to perform while being robust and providing exquisite control of the reaction …