COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
…, JE Shoemaker, J Zucker, K Oxford… - Molecular systems …, 2021 - embopress.org
We need to effectively combine the knowledge from surging literature with complex datasets
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
to propose mechanistic models of SARS‐CoV‐2 infection, improving data interpretation and …
[HTML][HTML] Protein coding content of the ULb′ region of wild-type rhesus cytomegalovirus
KL Oxford, MK Eberhardt, KW Yang, L Strelow, S Kelly… - Virology, 2008 - Elsevier
A recent comparison of two rhesus cytomegalovirus (RhCMV) genomes revealed that the
region at the right end of the U L genome component (U L b′) undergoes genetic alterations …
region at the right end of the U L genome component (U L b′) undergoes genetic alterations …
Open reading frames carried on UL/b′ are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys
Implicit with the use of animal models to test human cytomegalovirus (HCMV) vaccines is
the assumption that the viral challenge of vaccinated animals reflects the anticipated virus-host …
the assumption that the viral challenge of vaccinated animals reflects the anticipated virus-host …
Vaccine-induced control of viral shedding following rhesus cytomegalovirus challenge in rhesus macaques
…, A Dasgupta, Z Li, KA Schmidt, KL Oxford… - Journal of …, 2011 - Am Soc Microbiol
The use of animal models of human cytomegalovirus (HCMV) infection is critical to refine
HCMV vaccine candidates. Previous reports have demonstrated that immunization of rhesus …
HCMV vaccine candidates. Previous reports have demonstrated that immunization of rhesus …
[HTML][HTML] The interplay between immune maturation, age, chronic viral infection and environment
KL Oxford, MGA dela Pena-Ponce, K Jensen… - Immunity & …, 2015 - Springer
Background The worldwide increase in life expectancy has been associated with an increase
in age-related morbidities. The underlying mechanisms resulting in immunosenescence …
in age-related morbidities. The underlying mechanisms resulting in immunosenescence …
Leveraging structured biological knowledge for counterfactual inference: a case study of viral pathogenesis
Counterfactual inference is a useful tool for comparing outcomes of interventions on
complex systems. It requires us to represent the system in form of a structural causal model, …
complex systems. It requires us to represent the system in form of a structural causal model, …
[HTML][HTML] Human herpes simplex virus type 1 in confiscated gorilla
KVK Gilardi, KL Oxford, D Gardner-Roberts… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
In 2007, we detected human herpes simplex virus type 1, which caused stomatitis, in a
juvenile confiscated eastern lowland gorilla (Gorilla beringei graueri) that had a high degree of …
juvenile confiscated eastern lowland gorilla (Gorilla beringei graueri) that had a high degree of …
Immunogenicity of a vaccine formulated with the Chlamydia trachomatis serovar F, native major outer membrane protein in a nonhuman primate model
To determine the ability of a vaccine formulated with the genital Chlamydia trachomatis, serovar
F, native major outer membrane protein (Ct-F-nMOMP), to induce systemic and mucosal …
F, native major outer membrane protein (Ct-F-nMOMP), to induce systemic and mucosal …
The landscape of viral proteomics and its potential to impact human health
KL Oxford, JP Wendler, JE McDermott… - Expert review of …, 2016 - Taylor & Francis
Introduction: Advances in mass spectrometry-based proteomic technologies are enhancing
studies of viral pathogenesis. Identification and quantification of host and viral proteins and …
studies of viral pathogenesis. Identification and quantification of host and viral proteins and …
Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection
…, SV Westmoreland, A Kaur, KL Oxford… - Journal of …, 2012 - Am Soc Microbiol
We previously reported that long-term rhesus cytomegalovirus (RhCMV) excretion in
infected macaques was related to UL/b′ coding content. Acute biopsy specimens of the …
infected macaques was related to UL/b′ coding content. Acute biopsy specimens of the …