In discussions on intestinal protection, the protective capacity of mucus has not been very
much considered. The progress in the last years in understanding the molecular nature of …

Mucin-type O-linked oligosaccharides (O-glycans) are primary components of the intestinal
mucins that form the mucus gel layer overlying the gut epithelium. Impaired expression of …

The colon epithelium is protected from the luminal microbes as recently revealed by an inner
firmly attached mucus layer impervious to bacteria and an outer loose mucus layer that is …

The mucus filling the human cervical opening blocks the entry to the uterus, but this has to
be relative and allow for the sperm to penetrate at ovulation. We studied this mucus, its …

The mouse intestinal mucus is mainly made up by the gel-forming Muc2 mucin and the stomach
surface mucus Muc5ac, both extensively O-glycosylated. The oligosaccharide diversity …

The involvement of host immunity in the gut microbiota-mediated colonization resistance to
Clostridioides difficile infection (CDI) is incompletely understood. Here, we show that …

The Human Proteome Organisation Human Disease Glycomics/Proteome Initiative recently
coordinated a multi-institutional study that evaluated methodologies that are widely used for …

The high-molecular-mass salivary mucin MG1, one of two major mucins produced by human
salivary glands, plays an important role in oral health by coating the tooth surface and by …

The heavily O-glycosylated mucin MUC2 constitutes the major protein in the mucosal layer
that acts as a physical barrier protecting the epithelial layer in the colon. In this study, Muc2 …

This study aimed to characterize human salivary glycoforms and the natural glycosylation
variation of the major ABO blood group bearing high molecular weight glycoprotein fraction …