Adaptive immunity is driven by the expansion, somatic hypermutation, and selection of B
cell clones. Each clone is the progeny of a single B cell responding to Ag, with diversified Ig …

Analyses of somatic hypermutation (SHM) patterns in B cell Ig sequences have important
basic science and clinical applications, but they are often confounded by the intrinsic biases of …

The partial success of tumor immunotherapy induced by checkpoint blockade, which is not
antigen-specific, suggests that the immune system of some patients contain antigen receptors …

The manufacturing of virus occurs at a modest scale in comparison to many therapeutic
proteins mainly because a gene therapy dose is typically only µg of vector. Although modest in …

Cancer immunotherapy by checkpoint blockade proves that an effective immune response
to a tumor can be induced clinically. However, little is known about the evolution of tumor-…

… Kris Adams …

The use of DNA data is ubiquitous across animal sciences. DNA may be obtained from an
organism for a myriad of reasons including identification and distinction between cryptic …

… The authors would like to express gratitude to the following individuals and organizations
for their significant contribution to this project: Kris Adams, Audra Adelberger, Katherine Anne …

As we began this book with Lucas Benitez’s reminder that ‘‘farmworkers are in desperate
need of...[a] decent wage, the right to organize without fear of retaliation,[and] the right to earn …

… Miriam Hansen Linda Madlung Julie Majkowski Roxanne Neat Bruce O'Brien Sue
Richardson Sandy Robbers David Stoeri Kathleen Thomson Kris Adams Wendt Marge Loch-Wouters …