The disialoganglioside GD2 is overexpressed on several solid tumors, and monoclonal
antibodies targeting GD2 have substantially improved outcomes for children with high-risk …

Pentraxins are a family of ancient innate immune mediators conserved throughout evolution.
The classical pentraxins include serum amyloid P component (SAP) and C-reactive protein, …

Activation of β-adrenoceptors in the basolateral complex of the amygdala (BLA) modulates
memory storage processes and long-term potentiation in downstream targets of BLA efferents…

Significance: Hematopoietic stem cells (HSCs) can sustain the production of blood throughout
one's lifetime. However, for proper self-renewal of its own population and differentiation to …

Macrophage-mediated programmed cell removal (PrCR) is a process essential for the
clearance of unwanted (damaged, dysfunctional, aged, or harmful) cells. The detection and …

Pentraxins are innate pattern recognition molecules whose major function is to bind microbial
pathogens or cellular debris during infection and inflammation and, by doing so, contribute …

C-reactive protein (CRP) is an important biomarker for inflammatory diseases. However, its
role in inflammation beyond complement-mediated pathogen clearance remains poorly …

Hematopoietic stem/progenitor cell (HSPC) interactions with the bone marrow microenvironment
are important for maintaining HSPC self-renewal and differentiation. In recent work, we …

Communication between acute myeloid leukemia (AML) and the bone marrow microenvironment
is known to control disease progression. Therefore, regulation of AML cell trafficking …

A principal challenge in treating acute myeloid leukemia (AML) is chemotherapy refractory
disease. As such, there remains a critical need to identify key regulators of chemotherapy …