SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

…, CA Nelson, PD Hall, M Jansen, K Shanmugarajah… - MBio, 2021 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently causing a
global pandemic. The antigen specificity of the antibody response mounted against this novel …

[HTML][HTML] Surgical care in low and middle-income countries: burden and barriers

R Ologunde, M Maruthappu, K Shanmugarajah… - International Journal of …, 2014 - Elsevier
Surgically correctable pathology accounts for a sizeable proportion of the overall global
burden of disease. Over the last decade the role of surgery in the public health agenda has …

[PDF][PDF] Profiling B cell immunodominance after SARS-CoV-2 infection reveals antibody evolution to non-neutralizing viral targets

…, ES Winkler, ML Madariaga, K Shanmugarajah… - Immunity, 2021 - cell.com
Dissecting the evolution of memory B cells (MBCs) against SARS-CoV-2 is critical for
understanding antibody recall upon secondary exposure. Here, we used single-cell sequencing to …

Clinical predictors of donor antibody titre and correlation with recipient antibody response in a COVID‐19 convalescent plasma clinical trial

…, JP Kress, K Shanmugarajah… - Journal of internal …, 2021 - Wiley Online Library
Background Convalescent plasma therapy for COVID‐19 relies on transfer of anti‐viral
antibody from donors to recipients via plasma transfusion. The relationship between clinical …

The role of disgust emotions in the observer response to facial disfigurement

K Shanmugarajah, S Gaind, A Clarke, PEM Butler - Body image, 2012 - Elsevier
Social intrusions by observers are commonly reported by those with disfiguring conditions.
This study examined the role of disgust emotions in the observer response. A group of …

[HTML][HTML] Harnessing the properties of dendritic cells in the pursuit of immunological tolerance

C Horton, K Shanmugarajah, PJ Fairchild - Biomedical journal, 2017 - Elsevier
The acquisition of self-perpetuating, immunological tolerance specific for graft alloantigens
has long been described as the “holy grail” of clinical transplantation. By removing the need …

Surgical safety checklists in developing countries

…, RP Ravindran, K Shanmugarajah… - … journal of surgery, 2014 - journals.lww.com
The World Health Organization Surgical Safety Checklist (WHO SSC) has demonstrated
efficacy in developed and developing countries alike. Recent increases in awareness of …

[HTML][HTML] Clinical outcomes of facial transplantation: a review

K Shanmugarajah, S Hettiaratchy, A Clarke… - International journal of …, 2011 - Elsevier
A total of 18 composite tissue allotransplants of the face have currently been reported. Prior
to the start of the face transplant programme, there had been intense debate over the risks …

Facial transplantation

K Shanmugarajah, S Hettiaratchy… - Current opinion in …, 2012 - journals.lww.com
The outcomes of facial transplantation thus far have been very encouraging. The development
of standardized tools to measure functional and psychological outcomes is required as …

[PDF][PDF] Nanotraps for the containment and clearance of SARS-CoV-2

…, AJ Edobor, J Fung, JS Donington, K Shanmugarajah… - Matter, 2021 - cell.com
SARS-CoV-2 enters host cells through its viral spike protein binding to angiotensin-converting
enzyme 2 (ACE2) receptors on the host cells. Here, we show that functionalized …