Most prior studies of primary diagnosis in surgical pathology using whole slide imaging (WSI)
versus microscopy have focused on specific organ systems or included relatively few cases…

The rapid acceptance of immunohistochemistry as an important and even indispensable
adjunct to morphological examination and diagnosis requires the modern anatomical pathology …

p16 INK4a has emerged as a valuable surrogate marker for high-risk human papillomavirus
infection and shows increased immunoexpression with worsening grades of cervical …

D2-40 is a commercially available monoclonal antibody directed against human podoplanin,
a transmembrane mucoprotein that is expressed in lymphatic endothelial cells. Since its …

Glypican-3 (GPC3) is a heparan sulfate proteoglycan that plays an important role in cell growth
and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a …

Recently, CRISPR-Cas technology has opened a new era of nucleic acid-based molecular
diagnostics. However, current CRISPR-Cas-based nucleic acid biosensing has a lack of the …

BACKGROUND A survey of the distribution of human papillomavirus (HPV) types across the
spectrum of cervical cytologic categories defined by the Bethesda 2001 guidelines was …

DNA detection plays an important role in the rapid screening of cancers and early diagnosis
of infectious diseases. Here, we developed a simple, versatile, electric field-enhanced (EFE)…

Integration of human papillomavirus (HPV) into the cell genome is considered to be an
important event in the progression of cervical neoplasia. p16 INK4a, also a useful biomarker of …

Background Sarcomatoid renal cell carcinomas (SRCC) are composed of two cell populations,
a sarcomatous component (SC) and a carcinomatous component (CC). SRCC are …