[HTML][HTML] Membrane pyrophosphatases from Thermotoga maritima and Vigna radiata suggest a conserved coupling mechanism

KM Li, C Wilkinson, J Kellosalo, JY Tsai… - Nature …, 2016 - nature.com
Membrane-bound pyrophosphatases (M-PPases), which couple proton/sodium ion transport
to pyrophosphate synthesis/hydrolysis, are important in abiotic stress resistance and in the …

Crystal structures of starch binding domain from Rhizopus oryzae glucoamylase in complex with isomaltooligosaccharide: Insights into polysaccharide binding …

CH Chu, KM Li, SW Lin, MDT Chang… - Proteins: Structure …, 2014 - Wiley Online Library
Glucoamylases are responsible for hydrolysis of starch and polysaccharides to yield β‐d‐glucose.
Rhizopus oryzae glucoamylase (RoGA) is composed of an N‐terminal starch binding …

Roles of the hydrophobic gate and exit channel in Vigna radiata pyrophosphatase ion translocation

JY Tsai, KZ Tang, KM Li, BL Hsu, YW Chiang… - Journal of molecular …, 2019 - Elsevier
Membrane-embedded pyrophosphatase (M-PPase) hydrolyzes pyrophosphate to drive ion (H
+ and/or Na + ) translocation. We determined crystal structures and functions of Vigna …

[HTML][HTML] Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation

…, C Wilkinson, SPD Harborne, A Turku, KM Li… - Structural …, 2017 - pubs.aip.org
Membrane-integral pyrophosphatases (mPPases) couple the hydrolysis of pyrophosphate (PP
i) to the pumping of Na+, H+, or both these ions across a membrane. Recently solved …

Integrative model to coordinate the oligomerization and aggregation mechanisms of CCL5

…, SP Chen, JY Li, PC Chen, YZ Lee, KM Li… - Journal of molecular …, 2020 - Elsevier
CC-type chemokine ligand 5 (CCL5) is involved in the pathogenesis of many inflammatory
conditions. Under physiological conditions, CCL5 oligomerization and aggregation are …

[HTML][HTML] Two Unique Ligand-Binding Clamps of Rhizopus oryzae Starch Binding Domain for Helical Structure Disruption of Amylose

…, YP Ci, WI Chou, YC Lee, YJ Sun, WY Chou, KM Li… - PLoS …, 2012 - journals.plos.org
The N-terminal starch binding domain of Rhizopus oryzae glucoamylase (RoSBD) has a
high binding affinity for raw starch. RoSBD has two ligand-binding sites, each containing a …

Solution structure of bilayer membrane-embedded proton-translocating pyrophosphatase revealed via small-angle X-ray scattering

O Shih, YQ Yeh, KF Liao, KM Li, JY Tsai, CC Li… - Materials Chemistry and …, 2023 - Elsevier
The conformations and compositions of a proton-translocating pyrophosphatase Vigna radiata
H + -PPase (VrPPase), stabilized by either detergent molecules or embedded in a lipid …

[HTML][HTML] Endogenous hydrogen sulfide as a mediator of vas deferens smooth muscle relaxation

J Li, Y Li, Y Du, K Mou, H Sun, Y Zang, C Liu - Fertility and sterility, 2011 - Elsevier
Cystathionine-lyase and cystathionine-synthase, both H2S-synthesizing enzymes, were
functionally expressed in the vas deferens of rat, mice, and human. Endogenous H2S …

Inter‐Vehicle Communication for the Next Generation of Intelligent Transport Systems: Trends in Geographic Ad Hoc Routing Techniques

X Diao, KM Mou, JJ Li, H Zhou - Vehicular Networks: Models …, 2013 - Wiley Online Library
This chapter focuses on the geographic routing techniques in a pure vehicular ad hoc network
(VANET). The routing is, of course, a basic, indispensable feature that must be supported …

[HTML][HTML] Relationship between miR‑7 expression and treatment outcomes with gefitinib in non‑small cell lung cancer

K Mou, W Gu, C Gu, J Zhang, W Qwang… - Oncology …, 2016 - spandidos-publications.com
The aim of the present study was to assess the effects of gefitinib chemotherapy on the serum
levels of miR‑7 in patients with non‑small cell lung cancer (NSCLC). A total of 126 patients …