User profiles for Kunihiro Ohta

Kunihiro Ohta

The University of Tokyo
Verified email at bio.cu-tokyo.ac.jp
Cited by 7339

[HTML][HTML] Ubc9-and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks

…, X Zhao, D Maeda, M Seki, T Enomoto, K Ohta… - Cell, 2006 - cell.com
The Ubc9 SUMO-conjugating enzyme and the Siz1 SUMO ligase sumoylate several repair
and recombination proteins, including PCNA. Sumoylated PCNA binds Srs2, a helicase …

[HTML][HTML] Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination

…, K Murakami‐Murofushi, T Shibata, K Ohta - The EMBO …, 1998 - embopress.org
In Saccharomyces cerevisiae, Mre11 protein is involved in both double‐strand DNA break (DSB)
repair and meiotic DSB formation. Here, we report the correlation of nuclease and DNA…

Stepwise chromatin remodelling by a cascade of transcription initiation of non-coding RNAs

…, T Miyoshi, K Kugou, CS Hoffman, T Shibata, K Ohta - Nature, 2008 - nature.com
Recent transcriptome analyses using high-density tiling arrays 1 , 2 , 3 and data from large-scale
analyses of full-length complementary DNA libraries by the FANTOM3 consortium 4 , 5 …

[HTML][HTML] Ino80 chromatin remodeling complex promotes recovery of stalled replication forks

K Shimada, Y Oma, T Schleker, K Kugou, K Ohta… - Current Biology, 2008 - cell.com
Background Chromatin remodeling complexes facilitate the access of enzymes that mediate
transcription, replication or repair of DNA by modulating nucleosome position and/or …

Changes in chromatin structure at recombination initiation sites during yeast meiosis.

K Ohta, T Shibata, A Nicolas - The EMBO journal, 1994 - embopress.org
Transient double‐strand breaks (DSBs) occur during Saccharomyces cerevisiae meiosis at
recombination hot spots and are thought to initiate most, if not all, homologous …

Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination

…, Y Kawasaki, T Shibata, H Masai, K Ohta - Genes & …, 2008 - genesdev.cshlp.org
Meiosis ensures genetic diversification of gametes and sexual reproduction. For successful
meiosis, multiple events such as DNA replication, recombination, and chromosome …

Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot

…, E Hartsuiker, H Murofushi, T Shibata, K Ohta - The EMBO …, 2004 - embopress.org
Histone acetyltransferases (HATs) and ATP‐dependent chromatin remodeling factors (ADCRs)
are involved in selective gene regulation via modulation of local chromatin configuration. …

Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord

…, P Greimel, A Inoue, T Nabetani, A Murayama, K Ohta… - Science, 2015 - science.org
Glycerophospholipids, the structural components of cell membranes, have not been considered
to be spatial cues for intercellular signaling because of their ubiquitous distribution. We …

Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres

…, Y Akamatsu, H Iwasaki, K Mizuno, K Ohta… - … and cellular biology, 2003 - Taylor & Francis
The Mre11-Rad50-Nbs1(Xrs2) complex and the Ku70-Ku80 heterodimer are thought to
compete with each other for binding to DNA ends. To investigate the mechanism underlying this …

In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

…, N Shiina, H Kosako, K Shiokawa, T Akiyama, K Ohta… - Nature, 1991 - nature.com
THE protein kinase MAP kinase, also called MAP2 kinase, is a serine/threonine kinase
whose activation and phosphorylation are induced by a variety of mitogens 1–6 , and which is …