The cranial neural crest generates a huge diversity of derivatives, including the bulk of
connective and skeletal tissues of the vertebrate head. How neural crest cells acquire such …

Sutures separate the flat bones of the skull and enable coordinated growth of the brain and
overlying cranium. The coronal suture is most commonly fused in monogenic …

Y-box binding protein-1 (YB-1) is a pleiotropic molecule that binds DNA to regulate genes
on a transcriptional level in the nucleus and binds RNA to modulate gene translation in the …

A novel tumor suppressor miR-1185-1 is involved in molecular regulation of CD24- and
SIRT1-related cancer stemness networks, marking it a potential therapeutic target in colorectal …

The specification of cartilage requires Sox9, a transcription factor with broad roles for
organogenesis outside the skeletal system. How Sox9 and other factors gain access to cartilage-…

Vertebrate sensory organs arise from epithelial thickenings called placodes. Along with neural
crest cells, cranial placodes are considered ectodermal novelties that drove evolution of …

The poor intrinsic repair capacity of mammalian joint cartilage likely contributes to the high
incidence of arthritis worldwide. Adult zebrafish can regenerate many structures that show …

After traumatic injury, healing of mammalian ligaments is typically associated with fibrotic
scarring as opposed to scar-free regeneration. In contrast, here we show that the ligament …

Osteoarthritis (OA) impacts hundreds of millions of people worldwide, with those affected
incurring significant physical and financial burdens. Injuries such as focal defects to the …

Social networking sites host more than one billion members. These sites feature countless
fan pages, containing product information for social media marketing. For this type of …