Protein kinase C (PKC) consists of a family of closely related enzymes highly concentrated
in the CNS. These enzymes respond to the second messengers calcium (Ca 2+ ) and …

Aqueous solution of S-nitrosoglutathione (GSNO) underwent spontaneous chemical
transformation that generated several glutathione derivatives including glutathione sulfonic acid (…

Neurogranin/RC3 is a neural-specific Ca 2+ -sensitive calmodulin (CaM)-binding protein
whose CaM-binding affinity is modulated by phosphorylation and oxidation. Here we show that …

In neurons, neurogranin (Ng) binds calmodulin (CaM), and its binding affinity is reduced by
increasing Ca 2+ , phosphorylation by PKC, or oxidation by oxidants. Ng concentration in the …

Neurogranin/RC3 is a protein that binds calmodulin and serves as a substrate for protein
kinase C. Neuronally distributed in the hippocampus and forebrain, neurogranin is highly …

Three forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase (EC 2.7.1.37)
were separated by hydroxylapatite column chromatography. These enzymes, …

Environmental enrichment is known to enhance hippocampal neurogenesis and cognitive
functions. Neurogranin (Ng), a specific substrate of protein kinase C (PKC), is abundantly …

Although the brains of patients with schizophrenia and bipolar disorder exhibit decreased
brain pH relative to those of healthy controls upon postmortem examination, it remains …

As a consequence of rising operating and labor costs, numerous manufacturing companies
in Taiwan have been closed or relocated overseas during the last two decades. Since 2003, …

Protein kinase C (PKC) enzyme family consists of the Ca 2+ -dependent and -independent
subgroups of phospholipid/diacylglycerol (DAG)-stimulated serine/threonine protein kinases. …