User profiles for Kyla Sask

Kyla Sask

McMaster University
Verified email at mcmaster.ca
Cited by 414

Polyurethane-based microfluidic devices for blood contacting applications

WI Wu, KN Sask, JL Brash, PR Selvaganapathy - Lab on a Chip, 2012 - pubs.rsc.org
Protein adsorption on PDMS surfaces poses a significant challenge in microfluidic devices
that come into contact with biofluids such as blood. Polyurethane (PU) is often used for the …

Modification of polyurethane surface with an antithrombin–heparin complex for blood contact: influence of molecular weight of polyethylene oxide used as a linker …

KN Sask, LR Berry, AKC Chan, JL Brash - Langmuir, 2012 - ACS Publications
Polyurethane (PU) was modified using isocyanate chemistry to graft polyethylene oxide (PEO)
of various molecular weights (range 300–4600). An antithrombin–heparin (ATH) covalent …

Immobilization of an antithrombin–heparin complex on gold: Anticoagulant properties and platelet interactions

KN Sask, WG McClung, LR Berry, AKC Chan, JL Brash - Acta Biomaterialia, 2011 - Elsevier
The anticoagulant properties and platelet interactions of gold surfaces modified with an
antithrombin–heparin (ATH) complex are reported. ATH was attached to gold through either a …

[PDF][PDF] Blood compatible polymers

S Alibeik, KN Sask - Functional Biopolymers, 2019 - researchgate.net
Medical devices made from polymeric materials come in contact with blood in a wide range
of applications, including stents, artificial vascular grafts, hemodialysis membranes …

Electron microscopy imaging applications of room temperature ionic liquids in the biological field: A review

LA DiCecco, A D'Elia, C Miller, KN Sask… - …, 2021 - Wiley Online Library
For biological imaging using electron microscopy (EM), the use of room‐temperature ionic
liquids (RTILs) has been proposed as an alternative to traditional lengthy preparation methods…

Functionalization of 3D Printed Scaffolds Using Polydopamine and Silver Nanoparticles for Bone-Interfacing Applications

…, LA DiCecco, Z Hosseinidoust, KN Sask… - ACS Applied Bio …, 2023 - ACS Publications
The prevention of bacterial colonization and the stimulation of osseointegration are two major
requirements for bone-interfacing materials to reduce the incidence of complications and …

Hybrid silicon-tellurium-dioxide DBR resonators coated in PMMA for biological sensing

…, HC Frankis, AP Knights, A Turak, KN Sask… - Biomedical Optics …, 2023 - opg.optica.org
We report on silicon waveguide distributed Bragg reflector (DBR) cavities hybridized with a
tellurium dioxide (TeO_2) cladding and coated in plasma functionalized poly (methyl …

Enhancement of protein immobilization on polydimethylsiloxane using a synergistic combination of polydopamine and micropattern surface modification

J Li, LN Barlow, KN Sask - Journal of Biomaterials Science …, 2023 - Taylor & Francis
Understanding protein interactions at biointerfaces is critical for the improved design of
biomaterials and medical devices. Polydimethylsiloxane (PDMS) is used for numerous device …

Surface modification with an antithrombin–heparin complex for anticoagulation: studies on a model surface with gold as substrate

KN Sask, I Zhitomirsky, LR Berry, AKC Chan, JL Brash - Acta Biomaterialia, 2010 - Elsevier
Gold was used as a substrate for immobilization of an antithrombin–heparin (ATH) covalent
complex to investigate ATH as a surface modifier to prevent blood coagulation. Three …

Functionalization of Polydimethylsiloxane with Diazirine-Based Linkers for Covalent Protein Immobilization

…, L Bi, SF Musolino, JE Wulff, KN Sask - ACS Applied Materials & …, 2023 - ACS Publications
Biomolecule attachment to solid supports is critical for biomedical devices, such as biosensors
and implants. Polydimethylsiloxane (PDMS) is commonly used for these applications due …