User profiles for Kyle T. David

Kyle T. David

Vanderbilt University
Verified email at vanderbilt.edu
Cited by 123

Global gradients in the distribution of animal polyploids

KT David - Proceedings of the National Academy of …, 2022 - National Acad Sciences
Whole genome duplications (WGDs) are one of the most dramatic mutations that can be
found in nature. The effects of WGD vary dramatically but can have profound impacts on an …

[HTML][HTML] Genomic adaptations to chemosymbiosis in the deep-sea seep-dwelling tubeworm Lamellibrachia luymesi

Y Li, MG Tassia, DS Waits, VE Bogantes, KT David… - Bmc Biology, 2019 - Springer
Background Symbiotic relationships between microbes and their hosts are widespread and
diverse, often providing protection or nutrients, and may be either obligate or facultative. …

Saccharomycotina yeasts defy long-standing macroecological patterns

KT David, MC Harrison, DA Opulente… - Proceedings of the …, 2024 - National Acad Sciences
The Saccharomycotina yeasts (“yeasts” hereafter) are a fungal clade of scientific, economic,
and medical significance. Yeasts are highly ecologically diverse, found across a broad …

[HTML][HTML] Pleistocene to holocene expansion of the black-belt cichlid in Central America, Vieja maculicauda (Teleostei: Cichlidae)

CD McMahan, L Ginger, M Cage, KT David… - PLoS …, 2017 - journals.plos.org
The distributions of many Northern Hemisphere organisms have been influenced by
fluctuations in sea level and climatic conditions during Pleistocene interglacial periods. These …

Functional and evolutionary integration of a fungal gene with a bacterial operon

L Sun, KT David, JF Wolters, SD Karlen… - Molecular Biology …, 2024 - academic.oup.com
Siderophores are crucial for iron-scavenging in microorganisms. While many yeasts can
uptake siderophores produced by other organisms, they are typically unable to synthesize …

Sequencing disparity in the genomic era

KT David, AE Wilson… - Molecular Biology and …, 2019 - academic.oup.com
Advances in sequencing technology have resulted in the expectation that genomic studies
will become more representative of organismal diversity. To test this expectation, we explored …

TIAMMAt: leveraging biodiversity to revise protein domain models, evidence from innate immunity

MG Tassia, KT David, JP Townsend… - … Biology and Evolution, 2021 - academic.oup.com
Sequence annotation is fundamental for studying the evolution of protein families, particularly
when working with nonmodel species. Given the rapid, ever-increasing number of species …

[HTML][HTML] Patterns of gene evolution following duplications and speciations in vertebrates

KT David, JR Oaks, KM Halanych - PeerJ, 2020 - peerj.com
Background Eukaryotic genes typically form independent evolutionary lineages through
either speciation or gene duplication events. Generally, gene copies resulting from speciation …

Unsupervised Deep Learning Can Identify Protein Functional Groups from Unaligned Sequences

KT David, KM Halanych - Genome Biology and Evolution, 2023 - academic.oup.com
Interpreting protein function from sequence data is a fundamental goal of bioinformatics.
However, our current understanding of protein diversity is bottlenecked by the fact that most …

Spatial proximity between polyploids across South American frog genera

KT David, KM Halanych - Journal of Biogeography, 2021 - Wiley Online Library
Aim Polyploids have been theorized to occur more frequently in environments that are subjected
to severe conditions or sudden disruptions. Here we test the expectation that polyploid …