Frontotemporal dementia and its subtypes: a genome-wide association study

…, S Bagnoli, I Piaceri, JE Nielsen, LE Hjermind… - The Lancet …, 2014 - thelancet.com
Background Frontotemporal dementia (FTD) is a complex disorder characterised by a broad
range of clinical manifestations, differential pathological signatures, and genetic variability. …

Diagnostic genetic testing for Huntington's disease

…, O Quarrell, EK Bijlsma, M Davis, LE Hjermind… - Practical …, 2015 - pn.bmj.com
Huntington’s disease (HD) is an inherited neurodegenerative disorder characterised by a
combination of motor abnormalities (chorea, dystonia, hypokinesia), cognitive impairment and …

[HTML][HTML] Missense dopamine transporter mutations associate with adult parkinsonism and ADHD

…, H Weinstein, A Galli, LE Hjermind… - The Journal of …, 2014 - Am Soc Clin Investig
Parkinsonism and attention deficit hyperactivity disorder (ADHD) are widespread brain
disorders that involve disturbances of dopaminergic signaling. The sodium-coupled dopamine …

Corticobasal and ataxia syndromes widen the spectrum of C9ORF72 hexanucleotide expansion disease

…, LH Pinborg, K Vestergaard, LE Hjermind… - Clinical …, 2013 - Wiley Online Library
Recently, a hexanucleotide ( GGGGCC ) repeat expansion in the first intron of C9ORF72
was reported as the cause of chromosome 9p21‐linked frontotemporal dementia‐amyotrophic …

A randomized double-blind crossover trial comparing subthalamic and pallidal deep brain stimulation for dystonia

L Schjerling, LE Hjermind, B Jespersen… - Journal of …, 2013 - thejns.org
Object The authors' aim was to compare the subthalamic nucleus (STN) with the globus
pallidus internus (GPi) as a stimulation target for deep brain stimulation (DBS) for medically …

Novel mutation in ATP13A2 widens the spectrum of Kufor‐Rakeb syndrome (PARK9)

…, S Bech, LH Pinborg, L Friberg, LE Hjermind… - Clinical …, 2012 - Wiley Online Library
Eiberg H, Hansen L, Korbo L, Nielsen IM, Svenstrup K, Bech S, Pinborg LH, Friberg L,
Hjermind LE, Olsen OR, Nielsen JE. Novel mutation in ATP13A2 widens the spectrum of Kufor‐…

Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease

…, C Ammitzbøll, IU Larsen, LE Hjermind… - Neurology …, 2016 - AAN Enterprises
LE Hjermind: research project conception and manuscript review and critique. F. Sellebjerg:
research project conception and organization, statistical analysis review and critique, and …

[HTML][HTML] Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1

…, N Nimsanor, TT Nielsen, G Waldemar, LE Hjermind… - Stem Cell Research, 2016 - Elsevier
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease
causing neural cell degeneration and brain atrophy and is considered to be the most common …

[HTML][HTML] A clinical classification acknowledging neuropsychiatric and cognitive impairment in Huntington's disease

T Vinther-Jensen, IU Larsen, LE Hjermind… - Orphanet journal of rare …, 2014 - Springer
Background Involuntary movements, neuropsychiatric symptoms, and cognitive impairment
are all part of the symptom triad in Huntington’s disease (HD). Despite the fact that …

Reduction in mitochondrial DNA copy number in peripheral leukocytes after onset of Huntington's disease

…, SA Sørensen, JE Nielsen, LE Hjermind… - Mitochondrion, 2014 - Elsevier
Huntington's disease (HD) is an inherited neurodegenerative disorder characterised by
movement disorder, cognitive symptoms and psychiatric symptoms with predominantly adult-…