… Of the 19 relatives with ILD, 13 (68%) were classified as having ILD on the basis of CT
evidence for definite fibrosis, whereas 6 (32%) relatives had ILA without definite fibrosis and a Dl …

In this study, we leveraged a combination of single cell RNAseq, cytometry by time of flight (CyTOF),
and flow cytometry to study the biology of a unique macrophage population in …

Background No medical treatment has proven efficacy for acute exacerbations of idiopathic
pulmonary fibrosis (AE-IPF), and this syndrome has a very high mortality. Based on data …

Screening for pulmonary fibrosis may help to identify early stages of the disease. We assessed
the psychological impact of screening undiagnosed first-degree relatives of patients with …

Although interstitial lung disease (ILD) causes significant morbidity and mortality in rheumatoid
arthritis (RA), it is difficult to predict the development or progression of ILD, emphasising …

Rationale: Interstitial lung disease (ILD) is both the most frequent and most severe lung
manifestation of rheumatoid arthritis (RA), affecting approximately 10-20% of RA patients. …

Rationale: Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) have high mortality
and are often refractory to the current standard of care for which the mainstay is …

Methods The Columbia University Medical Center institutional review board approved this
study (AAAR1916). Written informed consent was obtained from all participants. We enrolled …

Many patients with interstitial lung disease (ILD) develop pulmonary fibrosis, which can lead
to reduced quality of life and early mortality. Patients with fibrotic ILD often have …

Pulmonary fibrosis (PF) is the most common indication for lung transplantation, with the
proportion of adult lung transplants performed for interstitial lung disease (ILD) increasing from 38…