Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors

…, E de la Cruz-Hernandez, LA Herrera - Cancer treatment …, 2008 - Elsevier
Among many anticancer drugs collectively named “targeted or molecular therapies” epigenetic
drugs are clearly promising. Differently from other agents targeting a single gene product, …

[HTML][HTML] The promising role of miR-21 as a cancer biomarker and its importance in RNA-based therapeutics

…, RM Álvarez-Gómez, LA Herrera - … Therapy-Nucleic Acids, 2020 - cell.com
MicroRNAs are small noncoding transcripts that posttranscriptionally regulate gene
expression via base-pairing complementarity. Their role in cancer can be related to tumor …

Are metals dietary carcinogens?

E Rojas, LA Herrera, LA Poirier… - … /Genetic Toxicology and …, 1999 - Elsevier
Humans have been in contact with metals almost since the beginning of our existence. In
fact, one cannot even think on human evolution without considering the great role played by …

Frequency, risk factors, clinical characteristics, and outcomes of spontaneous pneumothorax in patients with coronavirus disease 2019: a case-control, emergency …

…, DMV Herrera, BMM Bautista, APN Valdés, LA Álvarez… - Chest, 2021 - Elsevier
… Luz (Cuenca): Félix González Martínez, Diana Moya Olmeda; (54) Hospital Nuestra Señora
del Prado de Talavera de la Reina (Toledo): Ricardo Juárez; (55) Hospital Universitario de …

[HTML][HTML] The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

…, C Arriaga-Canon, LA Herrera - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the support
of clinical-pathological data such as the sum of the Gleason score and serum levels PSA. …

Mitotic index and cell proliferation kinetics for identification of antineoplastic activity

E Rojas, LA Herrera, M Sordo, ME Gonsebatt… - Anti-Cancer …, 1993 - journals.lww.com
The mitotic index (MI) and cell proliferation kinetics (CPK) of human blood lymphocyte
cultures were determined to evaluate the effects of six antineoplastic drugs with well known …

Significant clinical impact of recurrent BRCA1 and BRCA2 mutations in Mexico

…, RM Alvarez‐Gómez, C Pérez‐Plasencia, LA Herrera… - Cancer, 2015 - Wiley Online Library
BACKGROUND Frequent recurrent mutations in the breast and ovarian cancer susceptibility
(BRCA) genes BRCA1 and BRCA2 among Hispanics, including a large rearrangement …

[HTML][HTML] Impact of diabetes and hyperglycemia on survival in advanced breast cancer patients

…, E Bargallo, A Mohar, LA Herrera - Journal of Diabetes …, 2012 - hindawi.com
Purpose. We examined the impact of diabetes and hyperglycemia on cancer-specific
survival of patients with metastatic or recurrent breast cancer (BC). Methods. We performed a …

[HTML][HTML] Association of air particulate pollution with bone loss over time and bone fracture risk: analysis of data from two independent studies

…, I Kloog, JM Zmuda, M Holick, LA Herrera… - The Lancet planetary …, 2017 - thelancet.com
Background Air particulate matter is a ubiquitous environmental exposure associated with
oxidation, inflammation, and age-related chronic disease. Whether particulate matter is …

[HTML][HTML] MicroRNAs in cervical cancer: evidences for a miRNA profile deregulated by HPV and its impact on radio-resistance

…, V García-Castillo, N Jacobo-Herrera, LA Herrera… - Molecules, 2014 - mdpi.com
Cervical carcinoma (CC) is one of the most common cancers and a leading cause of mortality
in women worldwide. Epidemiologic and experimental data have clearly demonstrated a …