Neuropeptides are a diverse class of signaling molecules in metazoans. They occur in all
animals with a nervous system and also in neuron-less placozoans. However, their origin has …

The complete genome sequence of the original isolate of the model actinomycete
Streptomyces lividans 66, also referred to as 1326, was deciphered after a combination of next-…

Pelagic larval stages are widespread across animals, yet it is unclear whether larvae were
present in the last common ancestor of animals or whether they evolved multiple times due to …

Natural products from microbes have provided humans with beneficial antibiotics for millennia.
However, a decline in the pace of antibiotic discovery exerts pressure on human health …

Neuropeptide signalling systems comprising peptide ligands and cognate receptors are
evolutionarily ancient regulators of physiology and behaviour. However, there are challenges …

… Luis Alfonso Yañez Guerra … Luis Alfonso Yañez Guerra … Dose–response curves were
fitted with a four-parameter curve using Prism 6 (GraphPad, La Jolla, CA, USA) based on data …

ASIC channels are bilaterian proton-gated sodium channels belonging to the large and
functionally-diverse Deg/ENaC family that also includes peptide- and mechanically-gated …

Neuropeptides are one of the largest and most diverse families of signaling molecules in
animals and, accordingly, they regulate many physiological processes and behaviors. Genome …

Somatostatin (SS) and allatostatin-C (ASTC) are inhibitory neuropeptides in chordates and
protostomes, respectively, which hitherto were identified as orthologs. However, …

Neuropeptides are diverse signaling molecules in animals commonly acting through G-protein
coupled receptors (GPCRs). Neuropeptides and their receptors underwent extensive …