The ventricular-subventricular zone (V-SVZ), which lies in the walls of the lateral ventricles (LV),
is the largest neurogenic niche within the adult brain. Whether radiographic contact with …

While molecular subgrouping has revolutionized medulloblastoma classification, the extent
of heterogeneity within subgroups is unknown. Similarity network fusion (SNF) applied to …

Background Patients with incomplete surgical resection of medulloblastoma are controversially
regarded as having a marker of high-risk disease, which leads to patients undergoing …

Objective Sports-related concussions and traumatic brain injury (TBI) represent a growing
public health concern. We reviewed the literature regarding equestrian-related brain injury, …

Purpose Posterior fossa ependymoma comprises two distinct molecular variants termed
EPN_PFA and EPN_PFB that have a distinct biology and natural history. The therapeutic value …

In cancer, recurrent somatic single-nucleotide variants—which are rare in most paediatric
cancers—are confined largely to protein-coding genes 1 , 2 – 3 . Here we report highly …

The Karnofsky Performance Scale (KPS) score is a widespread metric to stratify patient
prognosis and determine appropriate management in glioblastoma multiforme(GBM). Low …

… Dr Chambless reported receving consulting fees from Integra outside the submitted work.
Dr Osterman reported receiving grants from Microsoft, IBM, and GE Healthcare outside the …

Background Mass cytometry measures 36 or more markers per cell and is an appealing
platform for comprehensive phenotyping of cells in human tissue and tumor biopsies. While …

Atypical meningioma has an aggressive clinical course. Distinguishing atypical from benign
meningioma preoperatively could affect surgical planning and improve treatment outcomes. …