User profiles for L. E. Colbert
Lauren ColbertMD Anderson Cancer Center Verified email at mdanderson.org Cited by 1350 |
[HTML][HTML] Microbiome factors in HPV-driven carcinogenesis and cancers
Human papillomavirus (HPV) infections account for over 600,000 new cancer cases every
year [1]. HPV is implicated in approximately 70% of oropharyngeal cancers (OPCs), 90% of …
year [1]. HPV is implicated in approximately 70% of oropharyngeal cancers (OPCs), 90% of …
Pronecrotic mixed lineage kinase domain‐like protein expression is a prognostic biomarker in patients with early‐stage resected pancreatic adenocarcinoma
BACKGROUND Mixed lineage kinase domain‐like protein (MLKL) is a necrosome component
mediating programmed necrosis that may be an important determinant of cancer cell …
mediating programmed necrosis that may be an important determinant of cancer cell …
[HTML][HTML] Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation
…, KM Schmeler, NJ Ajami, J Wargo, LE Colbert… - Communications …, 2021 - nature.com
Diversity of the gut microbiome is associated with higher response rates for cancer patients
receiving immunotherapy but has not been investigated in patients receiving radiation …
receiving immunotherapy but has not been investigated in patients receiving radiation …
[PDF][PDF] Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring
Tumor microbiota can produce active metabolites that affect cancer and immune cell signaling,
metabolism, and proliferation. Here, we explore tumor and gut microbiome features that …
metabolism, and proliferation. Here, we explore tumor and gut microbiome features that …
Brachytherapy training survey of radiation oncology residents
SR Marcrom, JM Kahn, LE Colbert, CM Freese… - International Journal of …, 2019 - Elsevier
Purpose As brachytherapy utilization rates decline, we sought to evaluate the state of
brachytherapy training during radiation oncology residency. Methods and Materials US radiation …
brachytherapy training during radiation oncology residency. Methods and Materials US radiation …
Gut microbial diversity and genus-level differences identified in cervical cancer patients versus healthy controls
Objectives The aim of this study was to characterize variation in the gut microbiome of women
with locally advanced cervical cancer and compare it to healthy controls. Methods We …
with locally advanced cervical cancer and compare it to healthy controls. Methods We …
Biology of the radio-and chemo-responsiveness in HPV malignancies
In multiple anatomic sites, patients with cancers associated with the Human Papillomavirus (HPV)
experience better locoregional control and overall survival after radiotherapy and/or …
experience better locoregional control and overall survival after radiotherapy and/or …
Proton beam radiation as salvage therapy for bilateral colorectal liver metastases not amenable to second-stage hepatectomy
Background Bilobar colorectal liver metastases (CRLM), are now aggressively managed in
a multidisciplinary fashion with a two-stage hepatectomy; however, up to 30% of patients are …
a multidisciplinary fashion with a two-stage hepatectomy; however, up to 30% of patients are …
Microbial diversity and composition is associated with patient-reported toxicity during chemoradiation therapy for cervical cancer
…, TT Sims, K Schmeler, P Okhuysen, LE Colbert… - International Journal of …, 2020 - Elsevier
Purpose Patients receiving pelvic radiation for cervical cancer experience high rates of acute
gastrointestinal (GI) toxicity. The association of changes in the gut microbiome with bowel …
gastrointestinal (GI) toxicity. The association of changes in the gut microbiome with bowel …
CHD7 expression predicts survival outcomes in patients with resected pancreatic cancer
LE Colbert, AV Petrova, SB Fisher, BG Pantazides… - Cancer research, 2014 - AACR
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with poor outcomes
with current therapies. Gemcitabine is the primary adjuvant drug used clinically, but its …
with current therapies. Gemcitabine is the primary adjuvant drug used clinically, but its …