Epilepsy affects 65 million people worldwide, a third of whom have seizures that are resistant
to anti-epileptic medications. Some of these patients may be amenable to surgical therapy …

Patients with drug-resistant epilepsy often require surgery to become seizure-free. While
laser ablation and implantable stimulation devices have lowered the morbidity of these …

Importance A functional area associated with the piriform cortex, termedarea tempestas, has
been implicated in animal studies as having a crucial role in modulating seizures, but …

There has been an increasing effort to correlate electrophysiology data with imaging in
patients with refractory epilepsy over recent years. IEEG.org provides a free-access, rapidly …

Patients with drug-resistant focal epilepsy are often candidates for invasive surgical
therapies. In these patients, it is necessary to accurately localize seizure generators to ensure …

Brain network models derived from graph theory have the potential to guide functional
neurosurgery, and to improve rates of post-operative seizure freedom for patients with epilepsy. A …

Obstructive sleep apnea (OSA) is associated with extensive neurologic comorbidities. It is
hypothesized that the repeated nocturnal apneas experienced in patients with OSA may inhibit …

Network neuroscience applied to epilepsy holds promise to map pathological networks,
localize seizure generators, and inform targeted interventions to control seizures. However, …

Objective To provide a multi-atlas framework for automated hippocampus segmentation in
temporal lobe epilepsy (TLE) and clinically validate the results with respect to surgical …

Objective Fluorodeoxyglucose-positron emission tomography (FDG-PET) is an established,
independent, strong predictor of surgical outcome in refractory epilepsy. In this study, we …