S-palmitoylation describes the reversible attachment of fatty acids (predominantly palmitate)
onto cysteine residues via a labile thioester bond. This posttranslational modification …

Exocytosis is the process whereby intracellular fluid‐filled vesicles fuse with the plasma
membrane, incorporating vesicle proteins and lipids into the plasma membrane and releasing …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

Lipid rafts are microdomains present within membranes of most cell types. These membrane
microdomains, which are enriched in cholesterol and glycosphingolipids, have been …

S-palmitoylation is a reversible post-translational modification that occurs on diverse cellular
proteins. Palmitoylation can affect proteins in many different ways, including regulating …

S-palmitoylation is a posttranslational modification that regulates membrane–protein
interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many …

The relative insolubility of lipid rafts in cold non-ionic detergents is the most widely used
method to purify these fascinating membrane domains from intact cells or membranes. Most of …

Lovastatin treatment caused down-regulation of the insulin-responsive glucose transporter
4 (Glut4) and up-regulation of Glut1 in 3T3-L1 adipocytes. These changes in protein …

SNAP25 and SNAP23 are plasma membrane SNARE proteins essential for regulated
exocytosis in diverse cell types. Several recent studies have shown that these proteins are partly …

S-acylation is a major posttranslational modification, catalyzed by the zinc finger DHHC
domain containing (zDHHC) enzyme family. S-acylated proteins can be modified by different …