Chrysin (5,7-dihydroxyflavone) is a flavonoid isolated from plants, such as Passiflora coerulea,
Passiflora incarnata, and Matricaria chamomilla. This natural molecule exerts diverse …

Flavonoids are phenolic compounds found commonly in plants that protect them against the
negative effects of environmental insults. These secondary metabolites have been widely …

Zebrafish (Danio rerio) is a popular and valuable species used in many different biomedical
research areas. The complex behavior that fish exhibit in response to different stimuli allows …

In woman, surgical menopause is associated with anxiety and depression symptoms.
Ovariectomy in rats has been proposed as an experimental model of surgical menopause, but its …

The aim of this study was to compare the effects of acute (a single injection) and chronic (21
consecutive days) treatments with chrysin 2, 4, and 8 umol kg–1 on anxiety-like behavior …

Generalized anxiety disorder is one of the most common psychiatric disorders, affecting a
high percentage of human beings around the world. This emotional disorder possesses …

Anxiety is a mental disorder characterized by excessive concern about possible future threats
that, if prolonged, becomes a pathology that must be controlled through psychotherapy …

Depressive disorders are among the most disabling diseases experienced around the world,
and their incidence has significantly increased over the last few decades due to multiple …

5-Hydroxytryptamine-1A and 5-hydroxytryptamine-2A receptors have been widely related to
the mechanism of action of antidepressant drugs. However, the influence of the flavonoid …

The forced swim test (FST) was proposed by Porsolt et al.(1977a, b) as a relatively rapid test
to identify new compounds with potential antidepressant activity in rats and mice. In this test, …