User profiles for L. J. Smith
Lachlan SmithAssociate Professor, Department of Orthopaedic Surgery, University of Pennsylvania Verified email at pennmedicine.upenn.edu Cited by 3540 |
Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques
Pulse field gradient NMR methods have been used to determine the effective hydrodynamic
radii of a range of native and nonnative protein conformations. From these experimental data…
radii of a range of native and nonnative protein conformations. From these experimental data…
Understanding protein folding via free-energy surfaces from theory and experiment
The ability of protein molecules to fold into their highly structured functional states is one of
the most remarkable evolutionary achievements of biology. In recent years, our …
the most remarkable evolutionary achievements of biology. In recent years, our …
The Frontier Fields: survey design and initial results
…, P Royle, LJ Smith, LJ Storrie-Lombardi… - The Astrophysical …, 2017 - iopscience.iop.org
What are the faintest distant galaxies we can see with the Hubble Space Telescope (HST)
now, before the launch of the James Webb Space Telescope? This is the challenge taken up …
now, before the launch of the James Webb Space Telescope? This is the challenge taken up …
Long-range interactions within a nonnative protein
…, J Wirmer, E Duchardt, T Ueda, T Imoto, LJ Smith… - Science, 2002 - science.org
Protein folding and unfolding are coupled to a range of biological phenomena, from the
regulation of cellular activity to the onset of neurodegenerative diseases. Defining the nature of …
regulation of cellular activity to the onset of neurodegenerative diseases. Defining the nature of …
[HTML][HTML] Percent emphysema, airflow obstruction, and impaired left ventricular filling
Background Very severe chronic obstructive pulmonary disease causes cor pulmonale with
elevated pulmonary vascular resistance and secondary reductions in left ventricular filling, …
elevated pulmonary vascular resistance and secondary reductions in left ventricular filling, …
Instructor–learner interaction in online courses: The relative perceived importance of particular instructor actions on performance and satisfaction
VP Dennen, A Aubteen Darabi, LJ Smith - Distance education, 2007 - Taylor & Francis
This article examines the relative perceived importance of 19 instructor actions in online
courses according to both instructors and students. The instructor actions were culled from …
courses according to both instructors and students. The instructor actions were culled from …
Defect-Rich Ultrathin ZnAl-Layered Double Hydroxide Nanosheets for Efficient Photoreduction of CO2 to CO with Water.
…, GI Waterhouse, LZ Wu, CH Tung, LJ Smith… - … (Deerfield Beach, Fla …, 2015 - europepmc.org
Defect-rich ultrathin ZnAl-layered double hydroxide nanosheets are successfully prepared.
Under UV-vis irradiation, these nanosheets are superior efficient catalysts for the …
Under UV-vis irradiation, these nanosheets are superior efficient catalysts for the …
Degeneration and regeneration of the intervertebral disc: lessons from development
LJ Smith, NL Nerurkar, KS Choi… - Disease models & …, 2011 - journals.biologists.com
Degeneration of the intervertebral discs, a process characterized by a cascade of cellular,
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
biochemical, structural and functional changes, is strongly implicated as a cause of low back …
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks
…, T Sigsgaard, A Simpson, V Siroux, LJ Smith… - Nature …, 2018 - nature.com
We examined common variation in asthma risk by conducting a meta-analysis of worldwide
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of …
Realistic ionizing fluxes for young stellar populations from 0.05 to 2 Z⊙
LJ Smith, RPF Norris… - Monthly Notices of the …, 2002 - academic.oup.com
We present a new grid of ionizing fluxes for O and Wolf—Rayet (W—R) stars for use with
evolutionary synthesis codes and single-star H ii region analyses. A total of 230 expanding, non…
evolutionary synthesis codes and single-star H ii region analyses. A total of 230 expanding, non…