Hepatocellular carcinoma (HCC) is currently the sixth most common type of cancer with a
high mortality rate and an increasing incidence worldwide. Its etiology is usually linked to …

Twenty cases of papillary cystic tumor of the pancreas were studied (19 female patients, one
male patient; median age, 19.5 years). Most tumors developed in the head or body of the …

Gastrointestinal stromal tumours (GISTs) are the most common primary mesenchymal tumours
of the gastrointestinal tract. Most of them show activating mutations of the genes coding …

Purpose: Oncogenic gene fusions involving the 3′ region of ROS1 kinase have been
identified in various human cancers. In this study, we sought to characterize ROS1 fusion genes …

Hepatocellular carcinoma (HCC) is among the leading causes of cancer‐related death.
Despite the advances in diagnosis and management of HCC, the biology of this tumor remains …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and the second
most frequent cause of cancer-related mortality worldwide. The multikinase inhibitor sorafenib …

Several studies have shown that glypican 3 (GPC3) could be a useful diagnostic marker for
hepatocellular carcinoma (HCC) and for differentiating HCC from nonneoplastic and …

Background: A small subset (10–15%) of gastrointestinal stromal tumours (GISTs) lack
mutations in KIT and PDGFRA (wild-type GIST). Recently, a novel BRAF exon 15 mutation (V600E…

LGR4/5 receptors and their cognate RSPO ligands potentiate Wnt/β-catenin signalling and
promote proliferation and tissue homeostasis in epithelial stem cell compartments. In the liver…

The incidence of human papilloma virus (HPV) induced oropharyngeal squamous cell
carcinoma (OPSCC) increases in the western countries. These OPSCC show distinct molecular …