Principles of laboratory assessment of drug abuse liability and implications for clinical development
LP Carter, RR Griffiths - Drug and Alcohol dependence, 2009 - Elsevier
Abuse liability testing plays an important role in informing drug development, regulatory
processes, and clinical practice. This paper describes the current “gold standard” methodologies …
processes, and clinical practice. This paper describes the current “gold standard” methodologies …
Behavioral analyses of GHB: receptor mechanisms
LP Carter, W Koek, CP France - Pharmacology & therapeutics, 2009 - Elsevier
GHB is used therapeutically and recreationally, although the precise mechanism of action
responsible for its different behavioral effects is not entirely clear. The purpose of this review is …
responsible for its different behavioral effects is not entirely clear. The purpose of this review is …
Vertebrobasilar insufficiency: part 1: microsurgical treatment of extracranial vertebrobasilar disease
✓ Extracranial vertebrobasilar artery thrombo-occlusive disease may cause repetitive transient
ischemic episodes and, less frequently, brain-stem or cerebellar infarction. This report …
ischemic episodes and, less frequently, brain-stem or cerebellar infarction. This report …
Clinical vasospasm after subarachnoid hemorrhage: response to hypervolemic hemodilution and arterial hypertension.
IA Awad, LP Carter, RF Spetzler, M Medina… - Stroke, 1987 - Am Heart Assoc
Delayed neurologic deterioration from vasospasm remains the greatest cause of morbidity
and mortality following subarachnoid hemorrhage. The authors assess the incidence and …
and mortality following subarachnoid hemorrhage. The authors assess the incidence and …
Surgical management of large AVM's by staged embolization and operative excision
RF Spetzler, NA Martin, LP Carter, RA Flom… - Journal of …, 1987 - thejns.org
✓ A series of 20 patients with giant arteriovenous malformations (AVM's) managed with staged
embolization and surgical resection is presented. Complete excision was accomplished …
embolization and surgical resection is presented. Complete excision was accomplished …
Accurate de novo design of hyperstable constrained peptides
Naturally occurring, pharmacologically active peptides constrained with covalent crosslinks
generally have shapes that have evolved to fit precisely into binding pockets on their targets. …
generally have shapes that have evolved to fit precisely into binding pockets on their targets. …
Multiple intracranial aneurysms: determining the site of rupture
DG Nehls, RA Flom, LP Carter, RF Spetzler - Journal of neurosurgery, 1985 - thejns.org
✓ A retrospective hospital chart and radiograph review was performed of all patients with
multiple intracranial aneurysms seen over a 52-month period. Sixty-nine patients with a total of …
multiple intracranial aneurysms seen over a 52-month period. Sixty-nine patients with a total of …
[BOOK][B] Crop production: principles and practices.
SR Chapman, LP Carter - 1976 - cabidigitallibrary.org
Success in achieving increased productivity in crop plants can only be accomplished
through understanding how crops develop and grow, how various factors affect growth and …
through understanding how crops develop and grow, how various factors affect growth and …
Treatment of malignant brain tumors with focused ultrasound hyperthermia and radiation: results of a phase I trial
AN Guthkelch, LP Carter, JR Cassady… - Journal of Neuro …, 1991 - Springer
Hyperthermia delivered by scanned focused ultrasound was combined with external beam
radiation to treat 15 patients with primary malignant tumors of the brain. A preliminary …
radiation to treat 15 patients with primary malignant tumors of the brain. A preliminary …
Aneurysms of the basilar artery treated with circulatory arrest, hypothermia, and barbiturate cerebral protection
RF Spetzler, MN Hadley, D Rigamonti, LP Carter… - Journal of …, 1988 - thejns.org
✓ Complete circulatory arrest, deep hypothermia, and barbiturate cerebral protection are
efficacious adjuncts in the surgical treatment of selected giant intracranial aneurysms. These …
efficacious adjuncts in the surgical treatment of selected giant intracranial aneurysms. These …