The skin is a multi-layered organ, often displaying associated structures, that establishes a
protective interface between the organism and the surrounding environment. In mammals, the …

Genomes are dynamic biological units, with processes of gene duplication and loss triggering
evolutionary novelty. The mammalian skin provides a remarkable case study on the …

Melatonin, the hormone of darkness, is a peculiar molecule found in most living organisms.
Emerging as a potent broad-spectrum antioxidant, melatonin was repurposed into extra roles …

Mammalian spermatozoa are a notable example of metabolic compartmentalization. Energy
in the form of ATP production, vital for motility, capacitation, and fertilization, is subcellularly …

The rapid expansion of high-quality genome assemblies, exemplified by ongoing initiatives
such as the Genome-10K and i5k, demands novel automated methods to approach …

Programmed cell death is a vital process in the life cycle of organisms. Necroptosis, an
evolutionary form of programmed necrosis, contributes to the innate immune response by killing …

Lead (Pb) has been highlighted as a major pollutant of both terrestrial and aquatic ecosystems,
causing negative impacts to these environments. The concentration of Pb in plants has …

… absent or LQ annotations. Our initial analysis revealed that several genes annotated as LQ
were in … Yet, in the case of LQ tagged Ccl27 from Hipposideros armiger (great roundleaf bat), …

The ancestors of Cetacea underwent profound morpho-physiological alterations. By displaying
an exclusive aquatic existence, cetaceans evolved unique patterns of locomotor activity, …

… Given the prominence of DRD 5 LQ annotations in Cetacea … 5 gene annotation, without the
LQ tag, as well as Hippopotamus … of the NCBI non-LQ tagged mammalian DRD 5 orthologous …