The biophysical features of neurons shape information processing in the brain. Cortical
neurons are larger in humans than in other species, but it is unclear how their size affects …

The biophysical properties of neurons are the foundation for computation in the brain. Neuronal
size is a key determinant of single neuron input–output features and varies substantially …

Background Circadian clocks control cell cycle factors, and circadian disruption promotes
cancer. To address whether enhancing circadian rhythmicity in tumor cells affects cell cycle …

Mechanotransduction, the conversion of mechanical stimuli into electrical signals, is a
fundamental process underlying essential physiological functions such as touch and pain sensing…

… Beaulieu-Laroche and Harnett demonstrate that voltage clamp, the main approach to
investigate synaptic physiology, is ineffective for most synapses because they reside on electrically …

… Beaulieu-Laroche et al. perform nearsimultaneous calcium imaging of somatic and
dendritic activity to reveal that active dendritic integration is an integral feature of information …

Mechanotransduction, the conversion of mechanical stimuli into electrical signals, is a
fundamental process underlying several physiological functions such as touch and pain sensing, …

Mechanical forces play numerous roles in physiology. When an object contacts our skin, it
exerts a force that is encoded as touch or pain depending on its intensity. Likewise, sound …

… Finally, I want to thank my parents, Renée Beaulieu and Marc Laroche, as well as my two
sisters, Marie-Rose and Charlie Beaulieu-Laroche, for their love and support. …

… In summary, the findings by BeaulieuLaroche and colleagues show that powerful electrical
coupling exists between the soma and dendrites of layer 5 pyramidal neurons in mouse …